As placental mammals, the pregnant women and the fetus have intense and prolonged
interactions during gestation. There is increasing evidence that multiple molecular as well as …

A major challenge to treating diseases during pregnancy is that small molecule therapeutics
are transported through the placenta and incur toxicities to the developing fetus. The …

In this study, we performed small RNA library sequencing using human placental tissues to
identify placenta-specific miRNAs. We also tested the hypothesis that human chorionic villi …

Autism is a profound disorder of neurodevelopment with poorly understood biological
origins. A potential role for maternal autoantibodies in the etiology of some cases of autism …

Liver sinusoidal endothelial cells (LSECs) display a number of receptors for efficient uptake
of potentially injurious molecules. The receptors for the Fc portion of immunoglobulin G (IgG) …

The human placenta is required to be the anchor, the conduit and the controller during
pregnancy. The survival of the baby and its associated placenta is dependent upon the …

During the past decade there has been an explosion in the number of nanoparticulate drugs
or drug delivery systems being explored, developed and marketed for the treatment and …

The transplacental transfer of maternal Immunoglobulin G (IgG) to the fetus is critical for
protection against infectious diseases in the first year of life [1]. Maternal protective IgG is …

Chorionic villi in the human placenta serve as essential structures in fetomaternal
exchanges. According to the embryology and placentology literature, during the first …

The Fc gamma receptor IIB (FcγRIIB/CD32B) was generated million years ago during
evolution. It is the sole inhibitory receptor for IgG, and has long been associated with the …