Malnutrition as an enteric infectious disease with long-term effects on child development

RL Guerrant, RB Oriá, SR Moore, MOB Oriá… - Nutrition …, 2008 - academic.oup.com
Malnutrition is a major contributor to mortality and is increasingly recognized as a cause of
potentially lifelong functional disability. Yet, a rate-limiting step in achieving normal nutrition …

Oxygen metabolism and barrier regulation in the intestinal mucosa

LE Glover, JS Lee, SP Colgan - The Journal of clinical …, 2016 - Am Soc Clin Investig
Mucosal surfaces are lined by epithelial cells and provide an important barrier to the flux of
antigens from the outside. This barrier is provided at a number of levels, including epithelial …

[HTML][HTML] Zinc: an essential micronutrient

RB Saper, R Rash - American family physician, 2009 - ncbi.nlm.nih.gov
Zinc is an essential micronutrient for human metabolism that catalyzes more than 100
enzymes, facilitates protein folding, and helps regulate gene expression. Patients with …

Zinc enhances intestinal epithelial barrier function through the PI3K/AKT/mTOR signaling pathway in Caco-2 cells

Y Shao, PG Wolf, S Guo, Y Guo, HR Gaskins… - The Journal of …, 2017 - Elsevier
Zinc plays an important role in maintaining intestinal barrier function as well as modulating
cellular signaling recognition and protein kinase activities. The phosphatidylinositol 3-kinase …

Epithelial barriers in intestinal inflammation

LJ John, M Fromm, JD Schulzke - Antioxidants & redox signaling, 2011 - liebertpub.com
The gastrointestinal epithelium transports solutes and water between lumen and blood and
at the same time forms a barrier between these compartments. This highly selective and …

New insights into the role of zinc in the respiratory epithelium

AQ Truong‐Tran, J Carter, R Ruffin… - Immunology and cell …, 2001 - Wiley Online Library
Over the past 30 years, many researchers have demonstrated the critical role of zinc (Zn), a
group IIb metal, in diverse physiological processes, such as growth and development …

Structure, properties, and engineering of the major zinc binding site on human albumin

CA Blindauer, I Harvey, KE Bunyan, AJ Stewart… - Journal of Biological …, 2009 - ASBMB
Most blood plasma zinc is bound to albumin, but the structure of the binding site has not
been determined. Zn K-edge extended x-ray absorption fine structure spectroscopy and …

Changes in chicken intestinal zinc exporter mRNA expression and small intestinal functionality following intra-amniotic zinc-methionine administration

E Tako, PR Ferket, Z Uni - The Journal of nutritional biochemistry, 2005 - Elsevier
A 303-bp cDNA of intestinal zinc exporter (ZnT1) was isolated from chicken jejunum by
reverse transcriptase-polymerase chain reaction and sequenced, and showed 42 …

Zinc in gut‐brain interaction in autism and neurological Disorders

G Vela, P Stark, M Socha, AK Sauer… - Neural …, 2015 - Wiley Online Library
A growing amount of research indicates that abnormalities in the gastrointestinal (GI) system
during development might be a common factor in multiple neurological disorders and might …

Diarrheal Mechanisms and the Role of Intestinal Barrier Dysfunction in Campylobacter Infections

FD Lobo de Sá, JD Schulzke, R Bücker - … Infections: Towards a One …, 2021 - Springer
Campylobacter enteritis is the most common cause of foodborne bacterial diarrhea in
humans. Although various studies have been performed to clarify the pathomechanism in …