Next generation and other sequencing technologies in diagnostic microbiology and infectious diseases

EE Hilt, P Ferrieri - Genes, 2022 - mdpi.com
Next-generation sequencing (NGS) technologies have become increasingly available for
use in the clinical microbiology diagnostic environment. There are three main applications of …

Rapid genomic diagnosis of fungal infections in the age of next-generation sequencing

CC Tsang, JLL Teng, SKP Lau, PCY Woo - Journal of Fungi, 2021 - mdpi.com
Next-generation sequencing (NGS) technologies have recently developed beyond the
research realm and started to mature into clinical applications. Here, we review the current …

[HTML][HTML] Clinical impact of metagenomic next-generation sequencing of bronchoalveolar lavage in the diagnosis and management of pneumonia: a multicenter …

H Zhou, PMK Larkin, D Zhao, Q Ma, Y Yao, X Wu… - The Journal of Molecular …, 2021 - Elsevier
Rapid and accurate pathogen identification is necessary for appropriate treatment of
pneumonia. Here, we describe the use of shotgun metagenomic next-generation …

Review of clinical and laboratory diagnostics for coccidioidomycosis

IH McHardy, B Barker… - Journal of Clinical …, 2023 - Am Soc Microbiol
Coccidioidomycosis is a fungal disease associated with soil exposure that frequently goes
undiagnosed due at least in part to its nonspecific presentation and the lack of clinical …

Recognition of diagnostic gaps for laboratory diagnosis of fungal diseases: expert opinion from the Fungal Diagnostics Laboratories Consortium (FDLC)

SX Zhang, NE Babady, KE Hanson… - Journal of clinical …, 2021 - Am Soc Microbiol
Fungal infections are a rising threat to our immunocompromised patient population, as well
as other nonimmunocompromised patients with various medical conditions. However, little …

Next-generation sequencing applications for the study of fungal pathogens

S Jiang, Y Chen, S Han, L Lv, L Li - Microorganisms, 2022 - mdpi.com
Next-generation sequencing (NGS) has become a widely used technology in biological
research. NGS applications for clinical pathogen detection have become vital technologies …

Current insight into culture-dependent and culture-independent methods in discovering Ascomycetous Taxa

NN Wijayawardene, M Bahram, I Sánchez-Castro… - Journal of Fungi, 2021 - mdpi.com
Culture techniques are vital in both traditional and modern fungal taxonomy. Establishing
sexual–asexual links and synanamorphs, extracting DNA and secondary metabolites are …

Fusarium and Neocosmospora: fungal priority pathogens in laboratory diagnosis

V Sáenz, AF Lizcano Salas, J Gené… - Critical Reviews in …, 2024 - Taylor & Francis
Fusarium and Neocosmospora are two fungal genera recently recognized in the list of
fungal priority pathogens. They cause a wide range of diseases that affect humans, animals …

[HTML][HTML] Utilizing Next-Generation Sequencing: Advancements in the Diagnosis of Fungal Infections

S Naik, D Kashyap, J Deep, S Darwish, J Cross… - Diagnostics, 2024 - mdpi.com
Next-generation sequencing (NGS) has emerged as a promising tool for diagnosing fungal
infections. It enables the identification of a wide range of fungal species and provides more …

Fungal Integrated Histomolecular diagnosis using targeted next-generation sequencing on Formalin-fixed paraffin-embedded tissues

A Trecourt, M Rabodonirina, C Mauduit… - Journal of Clinical …, 2023 - Am Soc Microbiol
Histopathology is the gold standard for fungal infection (FI) diagnosis, but it does not provide
a genus and/or species identification. The objective of the present study was to develop …