Simple Summary Breast cancer is the most common cancer among women. It is estimated
that 2.3 million new cases of BC are diagnosed globally each year. Based on mRNA gene …

Zinc finger myeloid, nervy, and deformed epidermal autoregulatory factor 1-type containing
8 (Zinc finger MYND-type containing 8, ZMYND8) is a transcription factor, a histone H3 …

27-Hydroxycholesterol (27-HC) is the most abundant oxysterol that increases the risk of
breast cancer progression. However, little is known about epigenetic regulation of 27-HC …

Emerging evidence suggested that epigenetic regulators can exhibit both activator and
repressor activities in gene transcriptional regulation and disease development, such as …

Recent studies have revealed that chemokine-like factor-like MARVEL transmembrane
domain-containing family member 6 (CMTM6) promotes tumor progression and modulates …

Protein homeostasis is predominantly governed through post-translational modification
(PTM). UBE3B, identified as an oncoprotein, exhibits elevated protein levels in breast …

Breast cancer stem cells (BCSCs) mitigate oxidative stress to maintain their viability and
plasticity. However, the regulatory mechanism of oxidative stress in BCSCs remains unclear …

Purpose: Mutant isocitrate dehydrogenase 1 (mIDH1) alters the epigenetic regulation of
chromatin, leading to a hypermethylation phenotype in adult glioma. This work focuses on …

ZMYND8, an epigenetic regulator, was identified as a common oncogene across various
tumors. However, little was reported about the association between ZMYND8 and bladder …

Background Aberrant epigenetic remodeling events contribute to progression and
metastasis of breast cancer (Bca). The specific mechanims that epigenetic factors rely on to …