Accumulating research suggests that the tumor immune microenvironment (TIME) plays an
essential role in regulation of tumor growth and metastasis. The cellular and molecular …

Myeloid-derived suppressor cells (MDSCs) constitute a vast population of immature myeloid
cells implicated in various conditions. Most notably, their role in cancer is of great …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous population of immature
myeloid cells that accumulate in tumor-bearing hosts to reduce T cells activity and promote …

Metformin, an oral medicine broadly used for the treatment of type 2 diabetes, has been
found to significantly improve tumor incidence and survival in large-scale clinical analysis. In …

Myeloid-derived suppressor cells (MDSCs) are a heterogeneous group of immature cells
derived from bone marrow that play critical immunosuppressive functions in the tumor …

Myeloid-derived suppressor cells (MDSCs) are a group of cells that regulate the immune
response and exert immunosuppressive effects on various immune cells. Current studies …

Introduction Myeloid‐derived suppressor cells (MDSCs) are a heterogeneous cell
population with the ability to suppress immune responses. MDSCs usually cluster in cancer …

Simple Summary Long non-coding RNAs (lncRNA), which are often referred to as “Genomic
Dark Matter”, are emerging as critical molecules involved in the regulation of multiple …

Hepatocellular carcinoma (HCC) is one of the most prevalent malignancies. It has high
mortality and poor clinical outcomes, but the molecular mechanisms in the pathogenesis of …

Highlights•Non-coding RNA pool is now the key player fine-tuning gene regulation.•Role of
lncRNA in RNA based therapeutics-journey from concept to clinic.•lncRNAs remodels tumor …