Natural marine products: Anti-colorectal cancer in vitro and in vivo

N Han, J Li, X Li - Marine drugs, 2022 - mdpi.com
Colorectal cancer, a malignant tumor with high mortality, has a poor prognosis due to drug
resistance and toxicity in clinical surgery and chemotherapy. Thus, finding safer and more …

Echinacoside inhibited cardiomyocyte pyroptosis and improved heart function of HF rats induced by isoproterenol via suppressing NADPH/ROS/ER stress

YJ Ni, J Zhang, W Zhu, Y Duan… - Journal of Cellular and …, 2022 - Wiley Online Library
Prevalence of heart failure (HF) continues to rise over time and is a global difficult problem;
new drug targets are urgently needed. In recent years, pyroptosis is confirmed to promote …

Activation of endoplasmic reticulum stress by harmine suppresses the growth of esophageal squamous cell carcinoma

R Fan, S Wang, Y Wu, Y Feng, M Gao… - Phytotherapy …, 2023 - Wiley Online Library
The worldwide overall 5‐year survival rate of esophageal squamous cell carcinoma (ESCC)
patients is less than 20%, and novel therapeutic strategies for these patients are urgently …

Cancer and Obesity: Crosstalk Between Adipocytes and Cancer Cells in the Tumor Microenvironment as a New Target in Cancer Research

P de Juan-Maciá, M Losada-Echeberría, V Micol… - 2024 - Springer
This chapter discusses the impact of obesity on tumor progression, focusing specifically on
two types of cancer linked to this condition, namely, colorectal cancer (CRC) and breast …

Identification of chemosensitizing agents of colorectal cancer in Rauvolfia vomitoria using an NMR-based chemometric approach

WL Cui, DX Guo, N Wang, ZF Wang, JB Ji… - Frontiers in …, 2023 - frontiersin.org
Searching for new adjuvants of conventional chemotherapeutic approaches against
colorectal cancer cells is extremely urgent. In current research, a non-targeted analytical …