Placebo and nocebo effects: from observation to harnessing and clinical application

Y Tu, L Zhang, J Kong - Translational Psychiatry, 2022 - nature.com
Placebo and nocebo effects are salubrious benefits and negative outcomes attributable to
non-specific symbolic components. Leveraging advanced experimental and analytical …

Affect and emotions in placebo and nocebo effects: What do we know so far?

AL Geers, K Faasse, DA Guevarra… - Social and …, 2021 - Wiley Online Library
Once considered nuisance variance in clinical trials, placebo effects and nocebo effects are
now widely recognized as important and mutable psychobiological contributors to mental …

Harnessing the placebo effect to enhance emotion regulation effectiveness and choice

R Shafir, M Israel, L Colloca - Scientific Reports, 2023 - nature.com
The placebo effect demonstrates how positive expectancies shape the effectiveness of
various treatments. Across studies, placebo treatments are interventions (creams, pills, etc.) …

The effect of the model's social status on placebo analgesia induced by social observational learning

H Bieniek, P Bąbel - Pain Medicine, 2022 - academic.oup.com
Background Placebo analgesia can be induced by social observational learning. The aim of
this study was to determine whether this effect can be influenced by the social status of a …

[HTML][HTML] The optimal learning cocktail for placebo analgesia: a randomized controlled trial comparing individual and combined techniques

JHPA van Lennep, H van Middendorp… - The journal of pain, 2023 - Elsevier
This study investigated for the first time the effects of individual and combined application of
3 learning techniques (verbal suggestions, classical conditioning, and observational …

As different as fear and anxiety: Introducing the fear and anxiety model of placebo hypoalgesia and nocebo hyperalgesia.

D Rubanets, J Badzińska, S Honcharova… - Psychological …, 2025 - psycnet.apa.org
Research suggests that negative affective states, such as fear and anxiety that accompany
placebo treatment may be considered predictors of placebo hypoalgesia and nocebo …

Placebo hypoalgesia induced by operant conditioning: a comparative study on the effects of verbal, token-based, and social rewards and punishers

H Bieniek, P Bąbel - Scientific Reports, 2023 - nature.com
Operant conditioning was shown to be a mechanism of placebo hypoalgesia; however, only
verbal rewards and punishers were applied in the previous study. We aimed to induce …

The effect of unpredictability on the perception of pain: A systematic review and meta-analysis

F Pavy, J Zaman, W Van Den Noortgate, A Scarpa… - Pain, 2022 - journals.lww.com
Despite being widely assumed, the worsening impact of unpredictability on pain perception
remains unclear because of conflicting empirical evidence, and a lack of systematic …

Can observational learning reinforce open-label placebo hypoalgesia?

J Brączyk, P Bąbel - Pain, 2022 - journals.lww.com
Previous research has indicated that an open-label placebo can reduce pain in both healthy
participants and patients with chronic pain. Because nondeceptive placebos seem to be an …

Pain-related anxiety among adults with obesity and chronic pain: Relations with pain, opioid misuse, and mental health

AH Rogers, BY Kauffman, L Garey… - Behavioral …, 2022 - Taylor & Francis
Obesity affect a significant proportion of the population in the United States, and is
associated with numerous health consequences including anxiety, depression, and chronic …