Natural history of mesenchymal stem cells, from vessel walls to culture vessels

IR Murray, CC West, WR Hardy, AW James… - Cellular and Molecular …, 2014 - Springer
Mesenchymal stem/stromal cells (MSCs) can regenerate tissues by direct differentiation or
indirectly by stimulating angiogenesis, limiting inflammation, and recruiting tissue-specific …

Human mesenchymal stromal cells from different sources diverge in their expression of cell surface proteins and display distinct differentiation patterns

KC Elahi, G Klein, M Avci-Adali, KD Sievert… - Stem cells …, 2016 - Wiley Online Library
When germ‐free cell cultures became a laboratory routine, hopes were high for using this
novel technology for treatment of diseases or replacement of cells in patients suffering from …

Defined MSC exosome with high yield and purity to improve regenerative activity

JY Kim, WK Rhim, YI Yoo, DS Kim… - Journal of Tissue …, 2021 - journals.sagepub.com
Exosomes derived from mesenchymal stem cells (MSCs) have been studied as vital
components of regenerative medicine. Typically, various isolation methods of exosomes …

Umbilical cord mesenchymal stem cell transplantation in active and refractory systemic lupus erythematosus: a multicenter clinical study

D Wang, J Li, Y Zhang, M Zhang, J Chen, X Li… - Arthritis research & …, 2014 - Springer
Introduction In our present single-center pilot study, umbilical cord (UC)–derived
mesenchymal stem cells (MSCs) had a good safety profile and therapeutic effect in severe …

Mesenchymal stem or stromal cells: toward a better understanding of their biology?

U Lindner, J Kramer, J Rohwedel… - Transfusion Medicine and …, 2010 - karger.com
The adult bone marrow has been generally considered to be composed of hematopoietic
tissue and the associated supporting stroma. Within the latter compartment, a subset of cells …

Comparative characterization of cells from the various compartments of the human umbilical cord shows that the Wharton's jelly compartment provides the best source …

A Subramanian, CY Fong, A Biswas, A Bongso - PloS one, 2015 - journals.plos.org
The human umbilical cord (UC) is an attractive source of mesenchymal stem cells (MSCs)
with unique advantages over other MSC sources. They have been isolated from different …

Wharton's jelly mesenchymal stem cells as candidates for beta cells regeneration: extending the differentiative and immunomodulatory benefits of adult mesenchymal …

R Anzalone, M Lo Iacono, T Loria, A Di Stefano… - Stem Cell Reviews and …, 2011 - Springer
Mesenchymal stem cells (MSC) are uniquely capable of crossing germinative layers borders
(ie are able to differentiate towards ectoderm-, mesoderm-and endoderm-derived cytotypes) …

[HTML][HTML] Mesenchymal stromal cells from human perinatal tissues: From biology to cell therapy

K Bieback, I Brinkmann - World journal of stem cells, 2010 - ncbi.nlm.nih.gov
Cell-based regenerative medicine is of growing interest in biomedical research. The role of
stem cells in this context is under intense scrutiny and may help to define principles of organ …

Mesenchymal stem cells in the umbilical cord: phenotypic characterization, secretome and applications in central nervous system regenerative medicine

MM Carvalho, FG Teixeira, RL Reis… - Current stem cell …, 2011 - ingentaconnect.com
Mesenchymal Stem Cells (MSCs), have been defined and characterized by: 1) their ability to
adhere to plastic culture flasks; 2) the positive expression of CD105, CD73, CD90 …

Promising therapeutic strategies for mesenchymal stem cell‐based cardiovascular regeneration: from cell priming to tissue engineering

ST Ji, H Kim, J Yun, JS Chung… - Stem cells …, 2017 - Wiley Online Library
The primary cause of death among chronic diseases worldwide is ischemic cardiovascular
diseases, such as stroke and myocardial infarction. Recent evidence indicates that adult …