A proof-of-concept preclinical study using a novel thermal insulation device in a porcine kidney auto-transplantation model

L Ernst, Z Czigany, P Paschenda, M Schulz… - International Journal of …, 2022 - mdpi.com
Ischemia-reperfusion injury remains a fundamental problem during organ transplantation
logistics. One key technical factor is the rapid allograft rewarming during the time of vascular …

Protection from the second warm ischemic injury in kidney transplantation using an ex vivo porcine model and thermally insulating jackets

T Khan, J Kwarcinski, T Pang, A Hameed… - Transplantation …, 2021 - Elsevier
Background Kidney transplantation is the optimum treatment for kidney failure in carefully
selected patients. Technical surgical complications and second warm ischemic time (SWIT) …

The impact of combined warm and cold ischemia time on post-transplant outcomes

ME Foley, AJ Vinson, TAA Skinner… - … Journal of Kidney …, 2023 - journals.sagepub.com
Background: Prolonged warm ischemia time (WIT) and cold ischemia time (CIT) are
independently associated with post-transplant graft failure; their combined impact has not …

A Novel Cooling Device for Kidney Transplant Surgery

A Dergham, L Witherspoon, L Power… - Surgical …, 2024 - journals.sagepub.com
Background: Prolonged warm ischemia time (WIT) in kidney transplantation is associated
with numerous adverse outcomes including delayed graft function and decreased patient …

Impact of an intra-abdominal cooling device during open kidney transplantation in pigs

A Longchamp, RPH Meier, N Colucci, A Balaphas… - bioRxiv, 2019 - biorxiv.org
Background Kidney transplantation using deceased donors still suffers from high post-
operative dysfunction rate. During implantation into the recipient, the kidney rewarms. This …

Anastomosis time and outcomes after donation after circulatory death kidney transplantation

DC Cron, N Murakami, L Xiang… - Journal of the …, 2022 - journals.lww.com
BACKGROUND: At every stage in the transplantation process for a deceased-donor kidney,
time means ischemia. Donation after circulatory death (DCD) kidneys are already subject to …

Renal transplant anastomotic time–Every minute counts!

N Mahajan, MK Heer, PR Trevillian - Frontiers in Medicine, 2023 - frontiersin.org
The impact of anastomotic time in renal transplant is under recognized and not well studied.
It is one of the few controllable factors that affect the incidence of delayed graft function …

The Effect of Recipient Back-Table Duration on Graft Outcome of Deceased Donor Kidneys: A Single-Center Prospective Cohort Study

JS Slagter, E Rijkse, RF De Wilde, R Haen… - Journal of Clinical …, 2023 - mdpi.com
Background: Little is known about the influence of the duration of the kidney back-table
preparation period and kidney temperature on graft outcomes after transplantation. The aim …

Insulating jackets thermally protect kidneys in an ex vivo model of second warm ischemia

T Khan, J Kwarcinski, P Boughton, P Yoon… - Artificial …, 2023 - Wiley Online Library
Background Kidney transplantation is the current optimal treatment for suitable patients with
end‐stage renal disease. The second warm ischemic time (SWIT) is known to negatively …

Effectiveness of Thermal Barrier Bag for Prolonged Vascular Anastomosis in Kidney Transplantation

K Ide, H Sakai, R Nakano, Y Imaoka, N Tanimine… - Transplantation …, 2023 - Elsevier
Background In kidney transplantation (KT), efforts to minimize rewarming and optimize
anastomosis time during vascular anastomosis improve graft outcomes. We recently …