[HTML][HTML] Co-delivery of doxorubicin/sorafenib by DNA-decorated green ZIF-67-based nanocarriers for chemotherapy and hepatocellular carcinoma treatment

BF Far, MR Naimi-Jamal, H Daneshgar… - Environmental Research, 2023 - Elsevier
Abstract Zeolitic imidazolate framework-67 (ZIF-67) has been decorated with natural
biomaterials and DNA to develop a promising strategy and suitable and safe co-delivery …

[HTML][HTML] Isolation and characterization of bioactive lactoferrin from camel milk by novel pH-dependent method for large scale production

N Mahala, A Mittal, M Lal, US Dubey - Biotechnology Reports, 2022 - Elsevier
The present article exemplifies a novel method to isolate highly purified bioactive lactoferrin
from camel milk. Cytotoxicity of lactoferrin against the Hela cells was used to evaluate its …

[HTML][HTML] Bioengineered DNA-decorated UiO-66-based nanocarriers for combined administration of doxorubicin and sorafenib: Hepatocellular carcinoma treatment …

BF Far, MR Naimi-Jamal, H Daneshgar… - Alexandria Engineering …, 2024 - Elsevier
Natural biomaterials were used to decorate UiO-66-NH 2 to develop a platform for co-drug
delivery of doxorubicin and sorafenib as a cost-effective and easy way to use a drug delivery …

RSM-CCD optimized hollow mesoporous silica nanospheres encapsulating sorafenib induce mitochondrial membrane potential mediated apoptotic cell death in non …

S Mohapatra, P Bhakuni, SR Barman… - … and Mesoporous Materials, 2024 - Elsevier
Hollow mesoporous silica nanoparticles (HMSNs) are considered appealing nanovehicles
for drug delivery due to their exceptional drug loading and release potential. This study …

Evaluation of the cytotoxic activity of sorafenib‐loaded camel milk casein nanoparticles against hepatocarcinoma cells

A Mittal, N Mahala, NH Dhanawade… - Biotechnology …, 2024 - Wiley Online Library
Sorafenib, a multikinase inhibitor is used to treat hepatocellular and renal carcinoma.
However, a low solubility impedes its bioavailability and thus, effectiveness. This study aims …

Dentine tubule occlusion effect of hydrolyzed casein in a bioactive glass-based dental desensitizing gel

N Shokouhnejad, E Tamjid, S Hasannia - Journal of Dentistry, 2023 - Elsevier
Objectives The effectiveness of three different groups of polyethylene glycol (PEG)-based
gels containing powders on dentin hypersensitivity (DH) treatment were assessed and …

Pharmacokinetic and Biodistribution Studies of Camel Milk Casein Nanoparticles Loaded Sorafenib in Swiss Albino Mice

A Mittal, R Pradhan, N Mahala, C Shrivastava… - BioNanoScience, 2024 - Springer
Sorafenib, a multikinase inhibitor, is used for the treatment of advanced stages of hepatic
and renal carcinoma patients. However, sorafenib's low solubility, low bioavailability …

Studies on cytotoxic activity of Camel milk whey protein as a nutraceutical against HeLa cells

M Lal, N Mahala, A Mittal, A Ramdas, C Shrivastava… - 2023 - indianjournals.com
The present study was based on cytotoxic properties of camel milk and its whey against the
cervical cancer-derived cell line, HeLa. High concentrations of camel milk and whey were …

Chromatographic purification of proteins with cytotoxic potential from camel milk whey against cervical cancer cell line

N Mahala, A Mittal, M Lal, US Dubey - 2023 - indianjournals.com
The objective of the present work was to purify bioactive components from camel milk and
test them for antineoplastic properties. Camel milk was separated into casein and whey …

[PDF][PDF] Medicinal Potential of Camel Milk Lactoferrin

N Mahala, A Mittal, US Dubey - 2022 - drive.google.com
Camel milk is a rich source of protein with well-recognized medicinal properties to treat
various diseases. The objective of this work is to understand the role of camel milk lactoferrin …