Using miRNAs as diagnostic biomarkers for male infertility: Opportunities and challenges
A Vashisht, GK Gahlay - Molecular Human Reproduction, 2020 - academic.oup.com
The non-coding genome has been extensively studied for its role in human development
and diseases. MicroRNAs (miRNAs) are small non-coding RNAs, which can regulate the …
and diseases. MicroRNAs (miRNAs) are small non-coding RNAs, which can regulate the …
MicroRNAs in spermatogenesis dysfunction and male infertility: clinical phenotypes, mechanisms and potential diagnostic biomarkers
Z Shi, M Yu, T Guo, Y Sui, Z Tian, X Ni… - Frontiers in …, 2024 - frontiersin.org
Infertility affects approximately 10–15% of couples worldwide who are attempting to
conceive, with male infertility accounting for 50% of infertility cases. Male infertility is related …
conceive, with male infertility accounting for 50% of infertility cases. Male infertility is related …
Qualitative and quantitative assessment of sperm miRNAs identifies hsa-miR-9-3p, hsa-miR-30b-5p and hsa-miR-122-5p as potential biomarkers of male infertility and …
M Joshi, SW Andrabi, RK Yadav, SN Sankhwar… - Reproductive Biology …, 2022 - Springer
Background In contrast with the preceding stages of the germ cells, spermatozoa are
unusually rich in small non-coding RNAs in comparison to the coding RNAs. These small …
unusually rich in small non-coding RNAs in comparison to the coding RNAs. These small …
[HTML][HTML] MicroRNAs in combined spent culture media and sperm are associated with embryo quality and pregnancy outcome
Objective To identify differentially abundant miRNAs in sperm samples and spent culture
media (SCM) of embryos of different grade toward a prediction of pregnancy outcome …
media (SCM) of embryos of different grade toward a prediction of pregnancy outcome …
Association between sperm morphology and altered sperm microRNA expression
M Tomic, L Bolha, J Pizem, H Ban-Frangez… - Biology, 2022 - mdpi.com
Simple Summary Sperm morphology is usually determined subjectively, and studies
focused exclusively on sperm morphology are scarce. There is a global tendency to find …
focused exclusively on sperm morphology are scarce. There is a global tendency to find …
Secreted MicroRNA to predict embryo implantation outcome: from research to clinical diagnostic application
W Zhou, E Dimitriadis - Frontiers in Cell and Developmental Biology, 2020 - frontiersin.org
Embryo implantation failure is considered a leading cause of infertility and a significant
bottleneck for in vitro fertilization (IVF) treatment. Confirmed factors that lead to implantation …
bottleneck for in vitro fertilization (IVF) treatment. Confirmed factors that lead to implantation …
[HTML][HTML] Study of small non-coding RNA (miRNA) expression pattern of fertile/infertile male semen
YH Al-Mawlah, MN Al-Darraji… - Acta Informatica Medica, 2022 - ncbi.nlm.nih.gov
Background: Infertility is a serious health issue that affects people all around the world. One
of the most common reasons for male infertility is sperm abnormalities. Researchers and …
of the most common reasons for male infertility is sperm abnormalities. Researchers and …
Transcriptome analysis reveals spermatogenesis-related CircRNAs and LncRNAs in goat spermatozoa
Mammalian spermatozoa comprises both coding and non-coding RNAs, which are
traditionally believed to be a residual of spermatogenesis. The differential expression level …
traditionally believed to be a residual of spermatogenesis. The differential expression level …
Correlation between sperm micro ribonucleic acid-34b and-34c levels and clinical outcomes of intracytoplasmic sperm injection in men with male factor infertility
LY Yeh, RKK Lee, MH Lin, CH Huang… - International Journal of …, 2022 - mdpi.com
Few studies have examined the correlation between sperm miRNA levels and clinical
outcomes of intracytoplasmic sperm injection (ICSI). In this study, we aimed to assess the …
outcomes of intracytoplasmic sperm injection (ICSI). In this study, we aimed to assess the …
Small RNAs, spermatogenesis, and male infertility: a decade of retrospect
Small non-coding RNAs (sncRNAs), being the top regulators of gene expression, have been
thoroughly studied in various biological systems, including the testis. Research over the last …
thoroughly studied in various biological systems, including the testis. Research over the last …