Cartilage is a hydrated biomacromolecular fiber composite located at the ends of long bones
that enables proper joint lubrication, articulation, loading, and energy dissipation …

Polysaccharides offer a wealth of biochemical and biomechanical functionality that can be
used to develop new biomaterials. In mammalian tissues, polysaccharides often exhibit a …

The mechanical response of a biological material to applied forces reflects deformation
mechanisms occurring within a hierarchical architecture extending over several distinct …

Control over neuronal growth is a fundamental objective in neuroscience, cell biology,
developmental biology, biophysics, and biomedicine and is particularly important for the …

Thin films constituted of poly (l-lysine)(PLL) as polycation and of the anionic polysaccharides
hyaluronan (HA), chondroitin sulfate (CSA), and heparin (HEP) as polyanions with …

Publisher Summary This chapter provides an overview of the natural origin polymers that
are commercially available or currently being studied in different laboratories for tissue …

This review summarises recent developments in the application of natural and semi-
synthetic polymers for the delivery of sensitive drugs. Peptides, proteins and nucleic acids …

We report smart nanoprobe, hyaluronic acid (HA)-based nanocontainers containing miR-
34a beacons (bHNCs), for the intracellular recognition of miR-34a levels in metastatic breast …

In this study, we have measured the nanoscale compressive interactions between opposing
aggrecan macromolecules in near-physiological conditions, in order to elucidate the …

Glycosaminoglycans (GAGs), a category of linear, anionic polysaccharides, are ubiquitous
in the extracellular space, and important extrinsic regulators of cell function. Despite the …