Oxygen-derived free radicals and related oxidants are ubiquitous and short-lived
intermediates formed in aerobic organisms throughout life. These reactive species …

Peroxynitrite is the product of the diffusion-controlled reaction of nitric oxide and superoxide
radicals. Peroxynitrite, a reactive short-lived peroxide with ap K a of 6.8, is a good oxidant …

Peroxynitrite is formed by the very fast reaction of nitric oxide and superoxide radicals, a
reaction that kinetically competes with other routes that chemically consume or physically …

This is the second set of Handbook of Porphyrin Science. Porphyrins, phthalocyanines and
their numerous analogues and derivatives are materials of tremendous importance in …

Oxidative stress has become widely viewed as an underlying condition in a number of
diseases, such as ischemia–reperfusion disorders, central nervous system disorders …

The accumulation of myeloid‐derived suppressor cells (MDSC) in tumor‐bearing hosts is a
hallmark of malignancy‐associated inflammation and a major mediator for the induction of T …

Programmed necrosis or necroptosis is an inflammatory form of cell death that critically
requires the receptor-interacting protein kinase 3 (RIPK3). Here we showed that RIPK3 …

Chronic overnutrition and physical inactivity are major risk factors for insulin resistance and
type 2 diabetes. Recent research indicates that overnutrition generates an increase in …

Significance: Superoxide dismutase (SOD) enzymes are indispensable and ubiquitous
antioxidant defenses maintaining the steady-state levels of O2·−; no wonder, thus, that their …

Significance: After approximatelty three decades of research, two Mn (III) porphyrins (MnPs),
MnTE-2-PyP5+ (BMX-010, AEOL10113) and MnTnBuOE-2-PyP5+ (BMX-001), have …