[HTML][HTML] PD-1/PD-L1 pathway: current researches in cancer

Y Han, D Liu, L Li - American journal of cancer research, 2020 - ncbi.nlm.nih.gov
Cancer immunotherapy has been accompanied by promising results over the past few
years. Programmed Cell Death Protein 1 (PD-1) plays a vital role in inhibiting immune …

Long non-coding RNAs in cancer: implications for diagnosis, prognosis, and therapy

Y Qian, L Shi, Z Luo - Frontiers in medicine, 2020 - frontiersin.org
Long non-coding RNAs (lncRNAs) are major components of cellular transcripts that are
arising as important players in various biological pathways. They have received extensive …

Long noncoding RNAs: molecular modalities to organismal functions

JL Rinn, HY Chang - Annual review of biochemistry, 2020 - annualreviews.org
We have known for decades that long noncoding RNAs (lncRNAs) can play essential
functions across most forms of life. The maintenance of chromosome length requires an …

MALAT1 Long Non-Coding RNA: Functional Implications

G Arun, D Aggarwal, DL Spector - Non-coding RNA, 2020 - mdpi.com
The mammalian genome is pervasively transcribed and the functional significance of many
long non-coding RNA (lncRNA) transcripts are gradually being elucidated. Metastasis …

Long non-coding RNAs (lncRNAs); roles in tumorigenesis and potentials as biomarkers in cancer diagnosis

S Najafi, SH Khatami, M Khorsand, Z Jamali… - Experimental cell …, 2022 - Elsevier
New research has indicated that long non-coding RNAs (lncRNAs) play critical roles in a
broad range of biological processes, including the pathogenesis of many complex human …

LncRNA MALAT1 contributes to non-small cell lung cancer progression via modulating miR-200a-3p/programmed death-ligand 1 axis

S Wei, K Wang, X Huang, Z Zhao… - International journal of …, 2019 - journals.sagepub.com
This study was to investigate the expression correlation between long non-coding RNA
metastasis-associated lung adenocarcinoma transcript 1 (lncRNA MALAT1), miR-200a-3p …

LncRNA Malat1 suppresses pyroptosis and T cell-mediated killing of incipient metastatic cells

D Kumar, S Gurrapu, Y Wang, SY Bae, PR Pandey… - Nature Cancer, 2024 - nature.com
The contribution of antitumor immunity to metastatic dormancy is poorly understood. Here
we show that the long noncoding RNA Malat1 is required for tumor initiation and metastatic …

The roles of long noncoding RNAs in breast cancer metastasis

L Liu, Y Zhang, J Lu - Cell death & disease, 2020 - nature.com
Breast cancer is the most significant threat to female health. Breast cancer metastasis is the
major cause of mortality in breast cancer patients. To fully unravel the molecular …

MaTAR25 lncRNA regulates the Tensin1 gene to impact breast cancer progression

KC Chang, SD Diermeier, AT Yu, LD Brine… - Nature …, 2020 - nature.com
Misregulation of long non-coding RNA (lncRNA) genes has been linked to a wide variety of
cancer types. Here we report on Mammary Tumor Associated RNA 25 (MaTAR25), a nuclear …

Regulation of MALAT1 triple helix stability and in vitro degradation by diphenylfurans

A Donlic, M Zafferani, G Padroni, M Puri… - Nucleic acids …, 2020 - academic.oup.com
Small molecule-based modulation of a triple helix in the long non-coding RNA metastasis-
associated lung adenocarcinoma transcript 1 (MALAT1) has been proposed as an attractive …