Autophagy is a process in which intracellular components and dysfunctional organelles are
delivered to the lysosome for degradation and recycling. Autophagy has various …

Macroautophagy is an evolutionarily conserved process that delivers diverse cellular
contents to lysosomes for degradation. As our understanding of this pathway grows, so does …

Autophagy, a conserved catabolic process, plays an immensely significant role in a variety
of diseases. However, whether it imparts a protective function in diseases remains …

In 2008, we published the first set of guidelines for standardizing research in autophagy.
Since then, this topic has received increasing attention, and many scientists have entered …

Pathogen‐associated molecular pattern molecules (PAMP s) are derived from
microorganisms and recognized by pattern recognition receptor (PRR)‐bearing cells of the …

The lysosomal degradation pathway of autophagy has a crucial role in defence against
infection, neurodegenerative disorders, cancer and ageing. Accordingly, agents that induce …

Selective macroautophagy (autophagy) of ubiquitinated protein is implicated as a
compensatory mechanism of the ubiquitin-proteasome system. p62/SQSTM1 is a key …

Macroautophagy (autophagy) is a lysosomal degradation pathway for the breakdown of
intracellular proteins and organelles. Although constitutive autophagy is a homeostatic …

Autophagy is essential for neuronal homeostasis, and its dysfunction has been directly
linked to a growing number of neurodegenerative disorders. The reasons behind …

Autophagy allows cell survival during starvation through the bulk degradation of proteins
and organelles by lysosomal enzymes. However, the mechanisms responsible for the …