A regulação da homeostasia intra e extra-celular da glicose está diretamente relacionada
ao controle preciso da expressão dos genes que codificam as diferentes isoformas de …

Sugar transport through the plasma membrane is one of the most critical events in the
cellular transport of nutrients; for example, glucose has a central role in cellular metabolism …

Background Metabolic syndrome is characterized by insulin resistance, which is closely
related to GLUT4 content in insulin-sensitive tissues. Thus, we evaluated the GLUT4 …

There is increasing evidence that poor early growth confers an increased risk of type 2
diabetes, hypertension, and other features of the metabolic syndrome in later life. We …

The purpose of the current study was to test the hypothesis that the dipeptidyl peptidase IV
(DPPIV) inhibitor sitagliptin, which exerts anti-hyperglycemic and anti-hypertensive effects …

In the renal collecting duct (CD), water reabsorption depends on the presence of aquaporin-
2 (AQP2) in the apical membrane of principal cells. AQP2 expression and subcellular …

Para melhor compreender o papel de cada um dos elementos envolvidos na fisiopatologia
da obesidade e da resistência à insulina, pesquisadores utilizam-se de modelos …

Insulin resistance and hyperinsulinemia are common findings in patients with essential
hypertension. Recent evidence indicates that these impairments in glucose metabolism may …

Background The prostatic effects induced by arterial hypertension is very controversial and
its mechanism is unclear. High‐intensity interval training (HIIT) is an exercise considered to …

Para melhor compreender o papel de cada um dos elementos envolvidos na fisiopatologia
da obesidade e da resistência à insulina, pesquisadores utilizam-se de modelos …