Infertility rates and the number of couples seeking fertility care have increased worldwide
over the past few decades. Over 2.5 million cycles of assisted reproductive technologies are …

Simple Summary This review describes the mechanical and energetic processes which
underpin mammalian sperm motility as well as the mechanisms by which various agents …

Nearly half of all pregnancies are unintended; thus, existing family planning options are
inadequate. For men, the only choices are condoms and vasectomy, and most current efforts …

INTRODUCTION Microtubules are key components of the eukaryotic cytoskeleton. Although
they are involved in a wide variety of functions, microtubules are structurally highly similar …

Motile cilia are miniature, propeller-like extensions, emanating from many cell types across
the body. Their coordinated beating generates a directional fluid flow, which is essential for …

The flagella of mammalian sperm display non-planar, asymmetric beating, in contrast to the
planar, symmetric beating of flagella from sea urchin sperm and unicellular organisms. The …

Biohybrid micromotors propelled by motile cells are fascinating entities for autonomous
biomedical operations on the microscale. Their operation under physiological conditions …

The infertility of many couples rests on an enigmatic dysfunction of the man's sperm. To gain
insight into the underlying pathomechanisms, we assessed the function of the sperm …

Flagellar beating drives sperm through the female reproductive tract and is vital for
reproduction. Flagellar waves are generated by thousands of asymmetric molecular …

The molecular mechanism underlying asymmetric axonemal complexes in sperm flagella is
still largely unknown. Here, we showed that the knockout of the coiled-coil domain …