Pyridinium salts: from synthesis to reactivity and applications

S Sowmiah, JMSS Esperança, LPN Rebelo… - Organic Chemistry …, 2018 - pubs.rsc.org
Structurally diverse pyridinium salts are quite familiar structures in many natural products
and bioactive pharmaceuticals. Over the centuries, these privileged scaffolds have played …

Recent advances in the synthesis of piperidines: functionalization of preexisting ring systems

GQ Liu, T Opatz - Advances in Heterocyclic Chemistry, 2018 - Elsevier
The present review focuses on strategies for the construction of piperidines which have
appeared in the literature since 2003 through mid-2017. In a preceding chapter …

Quaternary N-(2-Pyridyl)-DABCO Salts: One-Pot in Situ Formation from Pyridine-N-oxides and Reactions with Nucleophiles: A Mild and Selective Route to Substituted N-(2 …

DI Bugaenko, MA Yurovskaya… - The Journal of Organic …, 2017 - ACS Publications
The N-(2-pyridyl)-N′-ethylpiperazines are important structural motifs in several medicinally
relevant compounds. Known synthetic methods toward these structures are multistep and …

Transition‐Metal‐Free Regioselective Alkylation of Quinoline N‐Oxides via Oxidative Alkyl Migration and C− C Bond Cleavage of tert‐/sec‐Alcohols

C Sen, SC Ghosh - Advanced Synthesis & Catalysis, 2018 - Wiley Online Library
An unprecedented C2‐alkylation of quinoline N‐oxide derivatives via C− C bond activation
of tert‐and sec‐alkyl alcohol is described using hypervalent iodine (III) reagent PhI (OAc) 2 …

Visible‐Light‐Induced C2 Alkylation of Heterocyclic N‐Oxides with N‐Hydroxyphthalimide Esters under Metal‐Free Conditions

PT Qin, J Sun, F Wang, JY Wang… - … Synthesis & Catalysis, 2020 - Wiley Online Library
A visible‐light‐induced site selective C− H alkylation of heterocyclic N‐oxides with N‐
hydroxyphthalimide esters was developed using Eosin Y as the photocatalyst in the …

Is There an Adduct of Pyridine N-Oxide and Boron Trifluoride in the Gaseous State? Gas Electron Diffraction vs Mass Spectrometry

IS Lebedev, NV Belova, NI Giricheva… - Inorganic …, 2024 - ACS Publications
A study of saturated vapor over the pyridine N-oxide-boron trifluoride (PyO-BF3) adduct was
carried out at T= 448 (5) K by a synchronous gas electron diffraction/mass spectrometry …

Regio-and stereodivergent allylic reductions of bicyclic piperidine enecarbamate derivatives

F Berti, A Menichetti, L Favero, F Marchetti… - The Journal of …, 2018 - ACS Publications
The particular nature of tetrahydropyrido [4, 3-e]-1, 4, 2-dioxazines of type 1 allows the regio-
and stereoselective obtainment of substituted N-carbamoyl tetrahydropyridines by common …

Transition-Metal-Free Enantioselective Reactions of Organomagnesium Reagents Mediated by Chiral Ligands

H Guyon, A Boussonniere, AS Castanet - Synthesis, 2018 - thieme-connect.com
Organomagnesium reagents are among the most important reagents in organic chemistry
because of their great utility in forming carbon–carbon bonds. Although most …

Transition-metal-free dehydrogenation coupling of pyridinium through a self-promoted hydride transfer process

W Shang, S Li, Y Ding, Z Pan, X Tong… - Organic Chemistry …, 2017 - pubs.rsc.org
A transition-metal-free intramolecular cross dehydrogenation coupling reaction of pyridinium
was developed. The C (sp2)–H/C (sp2)–H coupling reaction involved an unprecedented …

Six-Membered Ring Systems: Pyridine and Benzo Derivatives

TLS Kishbaugh, K Lehman - Progress in Heterocyclic Chemistry, 2017 - Elsevier
The pyridine scaffold is present in a number of natural products, biologically active materials,
as well as in materials with interesting physical–chemical properties. As such, their …