[HTML][HTML] Extracellular vesicle-loaded hydrogels for tissue repair and regeneration

Y Ju, Y Hu, P Yang, X Xie, B Fang - Materials Today Bio, 2023 - Elsevier
Extracellular vesicles (EVs) are a collective term for nanoscale or microscale vesicles
secreted by cells that play important biological roles. Mesenchymal stem cells are a class of …

[HTML][HTML] Small extracellular vesicles isolation and separation: Current techniques, pending questions and clinical applications

Y Jia, L Yu, T Ma, W Xu, H Qian, Y Sun, H Shi - Theranostics, 2022 - ncbi.nlm.nih.gov
Extracellular vesicles, especially small extracellular vesicles (sEVs) are now accepted as
important messengers in cell-to-cell communication and as a promising drug delivery …

Extracellular vesicles for tissue repair and regeneration: Evidence, challenges and opportunities

A Nagelkerke, M Ojansivu, L van der Koog… - Advanced drug delivery …, 2021 - Elsevier
Extracellular vesicles (EVs) are biological nanoparticles naturally secreted by cells, acting
as delivery vehicles for molecular messages. During the last decade, EVs have been …

Exosomes derived from platelet-rich plasma administration in site mediate cartilage protection in subtalar osteoarthritis

Y Zhang, X Wang, J Chen, D Qian, P Gao, T Qin… - Journal of …, 2022 - Springer
Subtalar osteoarthritis (STOA) is often secondary to chronic ankle sprains, which seriously
affects the quality of life of patients. Due to its etiology and pathogenesis was not studied …

Hydrogel-mediated sustained systemic delivery of mesenchymal stem cell-derived extracellular vesicles improves hepatic regeneration in chronic liver failure

S Mardpour, MH Ghanian… - … applied materials & …, 2019 - ACS Publications
Extracellular vesicles derived from mesenchymal stem cells (MSC-EVs) have been widely
reported as promising cell-free products that show therapeutic effects of the parental cells …

Controlled release of epigenetically-enhanced extracellular vesicles from a GelMA/nanoclay composite hydrogel to promote bone repair

K Man, IA Barroso, MY Brunet, B Peacock… - International journal of …, 2022 - mdpi.com
Extracellular vesicles (EVs) have garnered growing attention as promising acellular tools for
bone repair. Although EVs' potential for bone regeneration has been shown, issues …

Engineered extracellular vesicles: tailored-made nanomaterials for medical applications

K Man, MY Brunet, MC Jones, SC Cox - Nanomaterials, 2020 - mdpi.com
Extracellular vesicles (EVs) are emerging as promising nanoscale therapeutics due to their
intrinsic role as mediators of intercellular communication, regulating tissue development and …

[HTML][HTML] Injectable hyperbranched PEG crosslinked hyaluronan hydrogel microparticles containing mir-99a-3p modified subcutaneous ADSCs-derived exosomes was …

Z Yin, C Qin, S Pan, C Shi, G Wu, Y Feng, J Zhang… - Materials Today Bio, 2023 - Elsevier
Exosomes (Exos) secreted by adipose-derived stem cells (ADSCs) have shown potential in
alleviating osteoarthritis (OA). Previous studies indicated that infrapatellar fat pad (IPFP) …

Epigenetic reprogramming enhances the therapeutic efficacy of osteoblast‐derived extracellular vesicles to promote human bone marrow stem cell osteogenic …

K Man, MY Brunet… - Journal of …, 2021 - Wiley Online Library
Extracellular vesicles (EVs) are emerging in tissue engineering as promising acellular tools,
circumventing many of the limitations associated with cell‐based therapies. Epigenetic …

Extracellular vesicles: From bone development to regenerative orthopedics

OG Davies - Molecular Therapy, 2023 - cell.com
Regenerative medicine aims to promote the replacement of tissues lost to damage or
disease. While positive outcomes have been observed experimentally, challenges remain in …