COVID-19 and cancer: current challenges and perspectives

Z Bakouny, JE Hawley, TK Choueiri, S Peters, BI Rini… - Cancer cell, 2020 - cell.com
Patients with cancer have been disproportionately affected by the COVID-19 pandemic. This
effect has included the adverse outcomes in patients with cancer who develop COVID-19 …

Disseminated intravascular coagulation

S Gando, M Levi, CH Toh - Nature reviews Disease primers, 2016 - nature.com
Disseminated intravascular coagulation (DIC) is an acquired syndrome characterized by
widespread intravascular activation of coagulation that can be caused by infectious insults …

Cancer-associated pathways and biomarkers of venous thrombosis

Y Hisada, N Mackman - Blood, The Journal of the American …, 2017 - ashpublications.org
Cancer patients have an increased risk of venous thromboembolism (VTE). In this review,
we summarize common and cancer type–specific pathways of VTE in cancer patients …

How I treat disseminated intravascular coagulation

M Levi, M Scully - Blood, The Journal of the American Society …, 2018 - ashpublications.org
Disseminated intravascular coagulation (DIC) is a condition characterized by systemic
activation of coagulation, potentially leading to thrombotic obstruction of small and midsize …

Cancer and embolic stroke of undetermined source

BB Navi, SE Kasner, MSV Elkind, M Cushman… - Stroke, 2021 - Am Heart Assoc
One-quarter to one-third of ischemic strokes have no established mechanism after standard
diagnostic evaluation and are classified as embolic stroke of undetermined source (ESUS) …

Mechanisms and risk factors of thrombosis in cancer

A Falanga, L Russo, V Milesi, A Vignoli - Critical reviews in oncology …, 2017 - Elsevier
The close relationship between cancer and thrombosis is known since more than a century.
Venous thromboembolism (VTE) may be the first manifestation of an occult malignancy in an …

How to manage coagulopathies in critically ill patients

J Helms, T Iba, JM Connors, S Gando, M Levi… - Intensive care …, 2023 - Springer
Coagulopathy is a severe and frequent complication in critically ill patients, for which the
pathogenesis and presentation may be variable depending on the underlying disease …

[HTML][HTML] TCF7L2 promotes anoikis resistance and metastasis of gastric cancer by transcriptionally activating PLAUR

T Zhang, B Wang, F Su, B Gu, L Xiang… - … Journal of Biological …, 2022 - ncbi.nlm.nih.gov
Gastric cancer (GC) is the most common gastrointestinal malignant tumor, and distant
metastasis is a critical factor in the prognosis of patients with GC. Understanding the …

Combining two strategies to improve perfusion and drug delivery in solid tumors

T Stylianopoulos, RK Jain - Proceedings of the National …, 2013 - National Acad Sciences
Blood perfusion in tumors can be significantly lower than that in the surrounding normal
tissue owing to the leakiness and/or compression of tumor blood vessels. Impaired perfusion …

Risk of tumorigenicity in mesenchymal stromal cell–based therapies—bridging scientific observations and regulatory viewpoints

L Barkholt, E Flory, V Jekerle, S Lucas-Samuel… - Cytotherapy, 2013 - Elsevier
In the past decade, the therapeutic value of mesenchymal stromal cells (MSCs) has been
studied in various indications, thereby taking advantage of their immunosuppressive …