Analysis of protein phosphorylation and cellular signaling events by flow cytometry: techniques and clinical applications
Analysis of protein phosphorylation with flow cytometric techniques has emerged as a
powerful tool in the field of immunological signaling, allowing cellular subsets in complex …
powerful tool in the field of immunological signaling, allowing cellular subsets in complex …
Mapping normal and cancer cell signalling networks: towards single-cell proteomics
Oncogenesis and tumour progression are supported by alterations in cell signalling. Using
flow cytometry, it is now possible to track and analyse signalling events in individual cancer …
flow cytometry, it is now possible to track and analyse signalling events in individual cancer …
Involvement of Brca1 in S-Phase and G2-Phase Checkpoints after Ionizing Irradiation
B Xu, S Kim, MB Kastan - Molecular and cellular biology, 2001 - Taylor & Francis
Cell cycle arrests in the G1, S, and G2phases occur in mammalian cells after ionizing
irradiation and appear to protect cells from permanent genetic damage and transformation …
irradiation and appear to protect cells from permanent genetic damage and transformation …
Biological methods for cell-cycle synchronization of mammalian cells
PK Davis, A Ho, SF Dowdy - Biotechniques, 2001 - Taylor & Francis
Understanding the molecular and biochemical basis of cellular growth and division involves
the investigation of regulatory events that most often occur in a cell-cycle phase-dependent …
the investigation of regulatory events that most often occur in a cell-cycle phase-dependent …
Resveratrol Increases Nitric Oxide Synthase, Induces Accumulation of p53 and p21WAF1/CIP1, and Suppresses Cultured Bovine Pulmonary Artery EndothelialCell Proliferation …
Epidemiological studies have shown that the regular consumption of red wine may in part
account for the apparent compatibility of a high fat diet with a low incidence of coronary …
account for the apparent compatibility of a high fat diet with a low incidence of coronary …
RNAa is conserved in mammalian cells
Background RNA activation (RNAa) is a newly discovered mechanism of gene activation
triggered by small double-stranded RNAs termed 'small activating RNAs'(saRNAs). Thus far …
triggered by small double-stranded RNAs termed 'small activating RNAs'(saRNAs). Thus far …
Laser-scanning cytometry: a new instrumentation with many applications
Z Darzynkiewicz, E Bedner, X Li, W Gorczyca… - Experimental cell …, 1999 - Elsevier
The laser-scanning cytometer (LSC) is a microscope-based cytofluorometer which has
attributes of both flow and image cytometry. Laser-excited fluorescence emitted from …
attributes of both flow and image cytometry. Laser-excited fluorescence emitted from …
Spartan deficiency causes genomic instability and progeroid phenotypes
RS Maskey, MS Kim, DJ Baker, B Childs… - Nature …, 2014 - nature.com
Spartan (also known as DVC1 and C1orf124) is a PCNA-interacting protein implicated in
translesion synthesis, a DNA damage tolerance process that allows the DNA replication …
translesion synthesis, a DNA damage tolerance process that allows the DNA replication …
BRCA1 phosphorylation by Aurora-A in the regulation of G2 to M transition
M Ouchi, N Fujiuchi, K Sasai, H Katayama… - Journal of biological …, 2004 - ASBMB
Aurora-A/BTAK/STK15 localizes to the centrosome in the G 2-M phase, and its kinase
activity regulates the G 2 to M transition of the cell cycle. Previous studies have shown that …
activity regulates the G 2 to M transition of the cell cycle. Previous studies have shown that …
Material properties of phase-separated TFEB condensates regulate the autophagy-lysosome pathway
Very little is known about how the material properties of protein condensates assembled via
liquid–liquid phase separation (LLPS) are maintained and affect physiological functions …
liquid–liquid phase separation (LLPS) are maintained and affect physiological functions …