Platinum (Pt)-based anticancer drugs such as cisplatin have been used to treat various
cancers. However, they have some limitations including poor selectivity and toxicity towards …

While medicinal inorganic chemistry has been practised for over 5000 years, it was not until
the late 1800s when Alfred Werner published his ground-breaking research on coordination …

Hydroxyquinoline (8-HQ) is a significant heterocyclic scaffold in organic and analytical
chemistry because of the properties of chromophore and is used to detect various metal ions …

The small molecule anticancer agent cisplatin and its Pt (II) analogs carboplatin and
oxaliplatin are widely used to treat a variety of tumorigenic diseases. Despite their structural …

Cancer is one of the leading causes of death worldwide. Although several potential
therapeutic agents have been developed to efficiently treat cancer, some side effects can …

Since the discovery of anticancer activity of cisplatin and other transition metal complexes, a
lot of compounds have been reported as containing ligand (s) bearing its (their) own …

Both ruthenium-containing complexes and 8-quinolinoline compounds have emerged as a
potential novel agent for malignant tumor therapy. Here, three triphenylphosphine ruthenium …

A new class of nickel (II) oxyquinoline–bipyridine complexes, namely,[Ni (La1) 2
(Lb6)](Ni1),[Ni (La1) 2 (Lb2)]· CH3OH (Ni2),[Ni (La7) 2 (Lb11)]· 2H2O (Ni3),[Ni (La1) 2 …

Lysosomal cysteine peptidase cathepsin B (catB) is an important tumor-promoting factor
involved in tumor progression and metastasis representing a relevant target for the …

The purpose of this work was to screen the antitumor actions of two metal organoruthenium-
8-hydroxyquinolinato (Ru-hq) complexes to find a potential novel agent for bone, lung and …