Oral mucositis: the hidden side of cancer therapy

C Pulito, A Cristaudo, CL Porta, S Zapperi… - Journal of experimental …, 2020 - Springer
Inflammation response of epithelial mucosa to chemo-radiotherapy cytotoxic effects leads to
mucositis, a painful side effect of antineoplastic treatments. About 40% of the patients treated …

Practical guidance for the evaluation and management of drug hypersensitivity: specific drugs

AD Broyles, A Banerji, S Barmettler, CM Biggs… - The Journal of Allergy …, 2020 - Elsevier
Allergists and clinical immunologists around the world are increasingly faced with the task of
addressing drug allergy and hypersensitivity due to the increase in drug reactions …

Mitigating acute chemotherapy-associated adverse events in patients with cancer

NM Kuderer, A Desai, MB Lustberg… - Nature Reviews Clinical …, 2022 - nature.com
Despite the enthusiasm surrounding novel targeted agents and immunotherapies,
chemotherapy remains the mainstay treatment for most human malignancies, either alone or …

New frontiers in the pathobiology and treatment of cancer regimen-related mucosal injury

M Cinausero, G Aprile, P Ermacora, D Basile… - Frontiers in …, 2017 - frontiersin.org
Mucositis is a common complication of chemotherapy, radiotherapy and targeted agents. It
often affects compliance to anticancer therapies as it frequently causes schedule delays …

Management of oral and gastrointestinal mucosal injury: ESMO Clinical Practice Guidelines for diagnosis, treatment, and follow-up

DE Peterson, CB Boers-Doets… - Annals of …, 2015 - annalsofoncology.org
Oral and gastrointestinal mucositis caused by high-dose chemotherapy and/or radiation
continues to be an important clinical problem. Fortunately, there have been strategic …

Adjunctive treatments for the prevention of chemotherapy-and radiotherapy-induced mucositis

M Thomsen, L Vitetta - Integrative Cancer Therapies, 2018 - journals.sagepub.com
Background: Chemoradiotherapy-associated mucositis can manifest as pain, inflammation,
dysphagia, diarrhea, weight loss, rectal bleeding, and infection. Mucositis is a major dose …

Oral mucositis induced by anticancer therapies

S Al-Ansari, JAEM Zecha, A Barasch, J de Lange… - Current oral health …, 2015 - Springer
Oral mucositis induced by conventional cytotoxic cancer therapies is a common and
significant clinical problem in oncology. Mucositis symptoms, which include severe pain …

Oral mucosal changes induced by anticancer targeted therapies and immune checkpoint inhibitors

E Vigarios, JB Epstein, V Sibaud - Supportive Care in Cancer, 2017 - Springer
Abstract Development of biological targeted therapies and immune checkpoint inhibitors has
redefined the treatment for many cancers; however, the increasing use of new protocols has …

Mechanism-based management for mucositis: option for treating side effects without compromising the efficacy of cancer therapy

Y Kwon - OncoTargets and therapy, 2016 - Taylor & Francis
Mucositis is a major side effect induced by chemotherapy and radiotherapy. Although
mucositis is a leading cause of morbidity and mortality in cancer patients, management is …

Costs of oral complications of cancer therapies: estimates and a blueprint for future study

LS Elting, YC Chang - JNCI Monographs, 2019 - academic.oup.com
Oral complications of cancer treatment are common; however, their clinical and economic
importance is often underappreciated. We reviewed the literature on the economic …