Regulation of the one carbon folate cycle as a shared metabolic signature of longevity

A Annibal, RG Tharyan, MF Schonewolff, H Tam… - Nature …, 2021 - nature.com
The metabolome represents a complex network of biological events that reflects the
physiologic state of the organism in health and disease. Additionally, specific metabolites …

The role of metabolomics in informing strategies for improving photosynthesis

P Westhoff, APM Weber - Journal of Experimental Botany, 2024 - academic.oup.com
Photosynthesis plays a vital role in acclimating to and mitigating climate change, providing
food and energy security for a population that is constantly growing, and achieving an …

[HTML][HTML] High-dose folic acid supplementation results in significant accumulation of unmetabolized homocysteine, leading to severe oxidative stress in Caenorhabditis …

K Koseki, Y Maekawa, T Bito, Y Yabuta, F Watanabe - Redox Biology, 2020 - Elsevier
Using Caenorhabditis elegans as a model animal, we evaluated the effects of chronical
supplementation with high-dose folic acid on physiological events such as life cycle and egg …

Mass spectrometric characterization of cyclic dinucleotides (CDNs) in vivo

A Annibal, R Ripa, E Ballhysa, C Latza… - Analytical and …, 2021 - Springer
Cyclic dinucleotides (CDNs) are key secondary messenger molecules produced by cyclic
dinucleotide synthases that trigger various cellular signaling cascades from bacteria to …

Optimization of mass spectrometry settings for steroidomic analysis in young and old killifish

R Dabrowski, R Ripa, C Latza, A Annibal… - Analytical and …, 2020 - Springer
Steroids are essential structural components of cell membranes that organize lipid rafts and
modulate membrane fluidity. They can also act as signalling molecules that work through …

Comparison of Atmospheric Pressure Chemical Ionization and Electrospray Ionization Mass Spectrometry for the Direct Analysis of Hops Bittering Compounds

C Sherpa - 2024 - search.proquest.com
Hops acids are essential components in the beer brewing process containing alpha acids (α-
acids) and beta acids (β-acids) as the major hops bittering compounds. Quantifying these …