In the last two or three decades the emphasis on and applications of green chemical
principles, introduced some significant advances in organic synthesis, such as combinatorial …

Achieving effective pain management is one of the major challenges associated with
modern day medicine. Opioids, such as morphine, have been the reference treatment for …

Covering: up to the end of August 2007 The purpose of diversity-oriented synthesis is to
drive the discovery of small molecules with previously unknown biological functions. Natural …

Multicomponent reactions are excellent tools for rapid generation of small molecules with
broad chemical diversity and molecular complexity. Herein, a novel one‐pot multicomponent …

Small molecule diversity can be achieved in a single synthetic operation from bifunctional
substrates in the absence of additives and under the influence of microwaves with complete …

This comprehensive review summarizes the published literature data concerning the
intramolecular Diels–Alder reactions of vinylarenes (the IMDAV reaction) and alkynyl arenes …

Functionalized thiazoles are generated from the reaction of dimethyl acetylenedicarboxylate,
benzoylisothiocyanates, and primary amines and trialkyl phosphite in the presence of ZnO …

A Rhodium(I)-Catalyzed Demethylation−Cyclization of o-Anisole-Substituted Ynamides in the
Synthesis of Chiral 2-Amido Benzofurans | Organic Letters ACS ACS Publications C&EN CAS …

Over the last decade, Diversity-Oriented Synthesis (DOS) has become a new paradigm for
developing large collections of structurally diverse small molecules as probes to investigate …

In continuation of our program to discover new potential pesticidal agents, thirty-one
piperine analogs containing isoxazoline/pyrazoline scaffold were prepared, and confirmed …