[HTML][HTML] An update on vitamin D signaling and cancer

C Carlberg, A Muñoz - Seminars in cancer biology, 2022 - Elsevier
A low vitamin D status is associated with an increased risk of various cancers, such as of
colon, breast, prostate and hematological cells. The biologically most active vitamin D …

Vitamin D and cancer: an historical overview of the epidemiology and mechanisms

A Muñoz, WB Grant - Nutrients, 2022 - mdpi.com
This is a narrative review of the evidence supporting vitamin D's anticancer actions. The first
section reviews the findings from ecological studies of cancer with respect to indices of solar …

Vitamin D signalling pathways in cancer: potential for anticancer therapeutics

KK Deeb, DL Trump, CS Johnson - Nature reviews cancer, 2007 - nature.com
Epidemiological studies indicate that vitamin D insufficiency could have an aetiological role
in various human cancers. Preclinical research indicates that the active metabolite of vitamin …

Vitamin D and cancer: a review of molecular mechanisms

JC Fleet, M Desmet, R Johnson, Y Li - Biochemical Journal, 2012 - portlandpress.com
The population-based association between low vitamin D status and increased cancer risk
can be inconsistent, but it is now generally accepted. These relationships link low serum …

[HTML][HTML] Vitamin D and the risk for cancer: A molecular analysis

C Carlberg, E Velleuer - Biochemical Pharmacology, 2022 - Elsevier
Uncontrolled overgrowth of cells, such as in cancer, is an unavoidable risk in life that affects
nearly every second individual in industrialized countries. However, in part this risk can be …

Optimal vitamin D status for colorectal cancer prevention: a quantitative meta analysis

ED Gorham, CF Garland, FC Garland, WB Grant… - American journal of …, 2007 - Elsevier
BACKGROUND: Previous studies, such as the Women's Health Initiative, have shown that a
low dose of vitamin D did not protect against colorectal cancer, yet a meta-analysis indicates …

Mechanisms of action of vitamin D in colon cancer

G Ferrer-Mayorga, MJ Larriba, P Crespo… - The Journal of steroid …, 2019 - Elsevier
Colorectal cancer (CRC) is the neoplasia that is most frequently associated with vitamin D
deficiency in epidemiological and observational studies in terms of incidence and mortality …

Vitamin D and colorectal cancer: molecular, epidemiological and clinical evidence

R Dou, K Ng, EL Giovannucci, JAE Manson… - British Journal of …, 2016 - cambridge.org
In many cells throughout the body, vitamin D is converted into its active form calcitriol and
binds to the vitamin D receptor (VDR), which functions as a transcription factor to regulate …

Circulating 25-hydroxyvitamin d levels and survival in patients with colorectal cancer

K Ng, JA Meyerhardt, K Wu, D Feskanich… - Journal of Clinical …, 2008 - ascopubs.org
Purpose Higher plasma 25-hydroxyvitamin D3 (25 (OH) D) levels are associated with a
decreased incidence of colorectal cancer, but the influence of plasma 25 (OH) D on the …

Plasma vitamin D concentration influences survival outcome after a diagnosis of colorectal cancer

L Zgaga, E Theodoratou, SM Farrington… - Journal of Clinical …, 2014 - ascopubs.org
Purpose We investigated whether the plasma level of 25-hydroxyvitamin D (25-OHD) after a
diagnosis of colorectal cancer (CRC) influences survival outcome. Patients and Methods We …