During the early meiotic prophase, connections are established between chromosomes and cytoplasmic motors via a nuclear envelope bridge, known as a LINC (linker of …
B Burke - Current opinion in cell biology, 2018 - Elsevier
Meiosis is a key processes of sexual reproduction in eukaryotes. By combining two cell division cycles with a single round of DNA replication meiosis provides a mechanism to …
Studies on the Caenorhabditis elegans nucleus have provided fascinating insight to the organization and activities of eukaryotic cells. Being the organelle that holds the genetic …
The LINC complex is found in a wide variety of organisms and is formed by the transluminal interaction between outer-and inner-nuclear-membrane KASH and SUN proteins …
X Huang, P Cheng, C Weng, Z Xu… - Proceedings of the …, 2021 - National Acad Sciences
PIWI-interacting RNAs (piRNAs) play significant roles in suppressing transposons, maintaining genome integrity, and defending against viral infections. How piRNA source loci …
Understanding the structure and structure–function relationships of membrane proteins is a fundamental problem in biomedical research. Given the difficulties inherent to performing …
J Rohožková, L Hůlková, J Fukalová, P Flachs… - Nucleus, 2019 - Taylor & Francis
During meiosis, homologous chromosomes undergo a dramatic movement in order to correctly align. This is a critical meiotic event but the molecular properties of this …
The nucleolus has been studied for the past 200 years, leading it to be a well characterized membraneless organelle. It is responsible for many cellular functions, notably ribosome …
LINC complex proteins connect the nucleoskeleton to the cytoskeleton, which is an important link for processes such as maintaining epithelial cell polarization and …