Investigating the role of the microRNA-34/449 family in male infertility: a critical analysis and review of the literature
K Pantos, S Grigoriadis, P Tomara, I Louka… - Frontiers in …, 2021 - frontiersin.org
There is a great body of evidence suggesting that in both humans and animal models the
microRNA-34/449 (miR-34/449) family plays a crucial role for normal testicular functionality …
microRNA-34/449 (miR-34/449) family plays a crucial role for normal testicular functionality …
Current mechanistic perspectives on male reproductive toxicity induced by heavy metals
BO Anyanwu, OE Orisakwe - Journal of Environmental Science …, 2020 - Taylor & Francis
Environmental and occupational exposures to heavy metals have led to various deleterious
damages to the biological system of which infertility is one of them. Infertility is a global …
damages to the biological system of which infertility is one of them. Infertility is a global …
CircRNA role and circRNA-dependent network (ceRNET) in asthenozoospermia
F Manfrevola, T Chioccarelli, G Cobellis… - Frontiers in …, 2020 - frontiersin.org
The role of circRNA in reproduction is under investigation. CircRNAs are expressed in
human testis, spermatozoa (SPZ), and seminal plasma. Their involvement in embryo …
human testis, spermatozoa (SPZ), and seminal plasma. Their involvement in embryo …
Expression of SPAG7 and its regulatory microRNAs in seminal plasma and seminal plasma-derived extracellular vesicles of patients with subfertility
M Abu-Halima, LS Becker, MA Al Smadi, LS Kunz… - Scientific Reports, 2023 - nature.com
Seminal plasma contains a variety of extracellular vesicles (EVs) that deliver RNAs including
microRNAs (miRNAs) molecules. However, the roles of these EVs along with their delivered …
microRNAs (miRNAs) molecules. However, the roles of these EVs along with their delivered …
MicroRNA-targeting in male infertility: Sperm microRNA-19a/b-3p and its spermatogenesis related transcripts content in men with oligoasthenozoospermia
M Abu-Halima, LS Becker, BM Ayesh… - Frontiers in Cell and …, 2022 - frontiersin.org
Objective: To elucidate and validate the potential regulatory function of miR-19a/b-3p and its
spermatogenesis-related transcripts content in sperm samples collected from men with …
spermatogenesis-related transcripts content in sperm samples collected from men with …
MicroRNA‐targeting in spermatogenesis: Over‐expressions of microRNA‐23a/b‐3p and its affected targeting of the genes ODF2 and UBQLN3 in spermatozoa of …
M Abu‐Halima, A Belkacemi, BM Ayesh… - …, 2021 - Wiley Online Library
Background Male infertility is a multifactorial syndrome with diverse phenotypic
representations. MicroRNAs (miRNAs) are small, non‐coding RNAs that are involved in the …
representations. MicroRNAs (miRNAs) are small, non‐coding RNAs that are involved in the …
Perfluorooctane sulfonate induces suppression of testosterone biosynthesis via Sertoli cell-derived exosomal/miR-9-3p downregulating StAR expression in Leydig …
J Huang, H Ren, A Chen, T Li, H Wang, L Jiang… - Environmental …, 2022 - Elsevier
Perfluorooctane sulfonate (PFOS) is associated with male reproductive disorder, but the
related mechanisms are still unclear. In this study, we used in vivo and in vitro models to …
related mechanisms are still unclear. In this study, we used in vivo and in vitro models to …
Characterization of micro-RNA in women with different ovarian reserve
M Abu-Halima, LS Becker, BM Ayesh, SL Baus… - Scientific Reports, 2021 - nature.com
Women undergoing infertility treatment are routinely subjected to one or more tests of
ovarian reserve. Therefore, an adequate assessment of the ovarian reserve is necessary for …
ovarian reserve. Therefore, an adequate assessment of the ovarian reserve is necessary for …
Levels of seminal tRNA-derived fragments from normozoospermic men correlate with the success rate of ART
JB Grosso, L Zoff, KL Calvo, MB Maraval… - Molecular Human …, 2021 - academic.oup.com
Decreased fertility is becoming an important social and medical problem and the male factor
is involved in at least half of infertility cases. Since conventional semen analysis provides …
is involved in at least half of infertility cases. Since conventional semen analysis provides …
Optimization of microRNA acquirement from seminal plasma and identification of diminished seminal microRNA-34b as indicator of low semen concentration
M Eikmans, J DH Anholts, L Blijleven… - International Journal of …, 2020 - mdpi.com
About 10–15% of couples who want to conceive suffer from subfertility, while in 30% of these
cases, a male factor plays a role. Levels of particular microRNAs in seminal plasma …
cases, a male factor plays a role. Levels of particular microRNAs in seminal plasma …