A severe decline in child births has occurred over the past half century, which will lead to
considerable population declines, particularly in industrialized regions. A crucial question is …

It is well-established that testicular spermatozoa are immature and acquire motility and
fertilization capabilities during transit throughout the epididymis. The epididymis is a duct …

Diet might affect male reproductive potential, but the biochemical mechanisms involved in
the modulation of sperm quality remain poorly understood. While a Western diet is …

BACKGROUND A defining feature of sexual reproduction is the transmission of genomic
information from both parents to the offspring. There is now compelling evidence that the …

The most fundamental process for the perpetuation of a species is the transfer of information
from parent to offspring. Although genomic DNA contributes to the majority of the …

Sperm plasma membrane lipids are essential for the function and integrity of mammalian
spermatozoa. Various lipid types are involved in each key step within the fertilization …

The epididymis is responsible for post-testicular sperm maturation as it provides a favorable
environment for spermatozoa to gain the ability for movement and fertilization. The recent …

Spermatozoa acquire fertilization potential during passage through a highly specialized
region of the extratesticular ductal system known as the epididymis. In the absence of de …

Semen quality and fertility has declined over the last 50 years, corresponding to ever-
increasing environmental stressors. However, the cellular mechanisms involved and their …

Extracellular vesicles (EVs) are secreted cell‐derived membrane structures present in all
organisms across animal, bacterial, and plant phyla. These vesicles play important roles in …