Oxidative stress is at the forefront of Alzheimer disease (AD) research. While its implications
in the characteristic neurodegeneration of AD are vast, the most important aspect is that it …

Activation of the proto-oncogene c-fos in the brain was described initially almost a decade
ago and represents one of the most studied immediate early genes in the brain. Transient c …

The understanding of the foreign-body responses to implanted biomaterials would benefit
from the reconstruction of intracellular and intercellular signalling networks in the …

We report that prospectively isolated, human CNS stem cells grown as neurospheres (hCNS-
SCns) survive, migrate, and express differentiation markers for neurons and …

The effects of fasting-mimicking diet (FMD) cycles in reducing many aging and disease risk
factors indicate it could affect Alzheimer's disease (AD). Here, we show that FMD cycles …

Recent evidence suggests that neurotrophic factors that promote the survival or
differentiation of developing neurons may also protect mature neurons from neuronal …

Elevated levels of β-Amyloid (Aβ) are present in the brains of individuals with either the
sporadic or familial form of Alzheimer's disease (AD), and the deposition of Aβ within the …

The mechanisms of action of human synthetic and naturally secreted cell-derived amyloid β-
peptide (Aβ) 1–42 on the induction of long-term potentiation (LTP) were investigated in the …

There are many lines of evidence showing that oxidative stress and aberrant mitogenic
changes have important roles in the pathogenesis of Alzheimer's disease (AD). However …

Abstract Presenilin1 (PS1), a protein implicated in Alzheimer's disease (AD), forms
complexes with N-cadherin, a transmembrane protein with important neuronal and synaptic …