Mitochondria are dynamic, multifunctional cellular organelles that play a fundamental role in
maintaining cellular homeostasis. Keeping the quality of mitochondria in check is of …

Autophagy serves a dichotomous role in cancer and recent advances have helped delineate
the appropriate settings where inhibiting or promoting autophagy may confer therapeutic …

Autophagy is a cellular degradation process important for neuronal development and
survival. Neurons are highly polarized cells in which autophagosome biogenesis is spatially …

Processing of misfolded proteins is important in order for the cell to maintain its normal
functioning and homeostasis. Three systems control the quality of proteins: chaperone …

Autophagy and autophagy‐related processes are fundamentally important in human health
and disease. These processes are viewed primarily as cellular degradative pathways that …

BECLIN 1 is a central player in macroautophagy. AMBRA1, a BECLIN 1‐interacting protein,
positively regulates the BECLIN 1‐dependent programme of autophagy. In this study, we …

Objectives To systematically review findings of GWAS in schizophrenia (SZ) and in bipolar
disorder (BD); and to interpret findings, with a focus on identifying independent replications …

Stem cell proliferation, neuronal differentiation, cell survival, and migration in the central
nervous system are all important steps in the normal process of neurogenesis. These …

Neuroepithelial cells undergoing differentiation efficiently remodel their cytoskeleton and
shape in an energy-consuming process. The capacity of autophagy to recycle cellular …

Vici syndrome is a progressive neurodevelopmental multisystem disorder due to recessive
mutations in the key autophagy gene EPG5. We report genetic, clinical, neuroradiological …