Animal organoid models derived from farm and companion animals have great potential to
contribute to human health as a One Health initiative, which recognize a close inter …

Preclinical biomedical research is limited by the predictiveness of in vivo and in vitro models.
While in vivo models offer the most complex system for experimentation, they are also …

Developing precise species-specific in vitro models that closely resemble in vivo intestinal
tissues is essential for advancing our understanding of gastrointestinal physiology and …

Recent progress in bovine intestinal organoid research has expanded opportunities for
creating improved in vitro models to study intestinal physiology and pathology. However, the …

Ultrasmall gold nanoparticles (2 nm) easily penetrate the membranes of intestinal murine
epithelial cells (MODE‐K) and colorectal cancer cells (CT‐26). They are also taken up by 3D …

Salmonella enterica serovar Dublin (S. Dublin) is an important enteric pathogen affecting
cattle and poses increasing public health risks. Understanding the pathophysiology and host …

The Caliciviridae are a family of viruses with a single-stranded, non-segmented RNA
genome of positive polarity. The ongoing discovery of caliciviruses has increased the …

Organoids are in vitro organ-like structures that faithfully recapitulate many characteristics of
a specific organ. During the past decades, major progress has been accomplished in …

A healthy intestine plays an important role in the growth and development of farm animals. In
small intestine, Paneth cells are well known for their regulation of intestinal microbiota and …

The gastrointestinal tract is a remarkable example of complex biology, with a constant
dialogue between the intestinal epithelium, in close contact with the microbiota, and the …