Modulation of Toll-like receptor 1 intracellular domain structure and activity by Zn2+ ions

VA Lushpa, MV Goncharuk, C Lin, AO Zalevsky… - Communications …, 2021 - nature.com
Toll-like receptors (TLRs) play an important role in the innate immune response. While a lot
is known about the structures of their extracellular parts, many questions are still left …

TIR domains of TLR family-from the cell culture to the protein sample for structural studies

VA Lushpa, MV Goncharuk, IA Talyzina, AS Arseniev… - Plos one, 2024 - journals.plos.org
Toll-like receptors (TLRs) are key players in the innate immune system. Despite the great
efforts in TLR structural biology, today we know the spatial structures of only four human TLR …

[PDF][PDF] Changes in the structure and dynamics of the intracellular domain of Toll-like receptors 1 under the action of Zn2+

VA Lushpa, MV Goncharuk, AO Zalevsky… - … Biology (BGRS/SB …, 2022 - scholar.archive.org
1 Moscow Institute of Physics and Technology (national research university), Moscow,
Russia 2 Shemyakin–Ovchinnikov Institute of Bioorganic Chemistry, RAS, Moscow, Russia 3 …