Tolerogenic dendritic cells in organ transplantation

J Ochando, F Ordikhani, S Jordan, P Boros… - Transplant …, 2020 - Wiley Online Library
Dendritic cells (DC s) are specialized cells of the innate immune system that are
characterized by their ability to take up, process and present antigens (Ag) to effector T cells …

Heme oxygenase-1 as a modulator of intestinal inflammation development and progression

VP Sebastián, GA Salazar… - Frontiers in …, 2018 - frontiersin.org
Heme Oxygenase 1 (HMOX1) is an enzyme that catalyzes the reaction that degrades the
heme group contained in several important proteins, such as hemoglobin, myoglobin, and …

Regulatory T cell-mediated anti-inflammatory effects promote successful tissue repair in both indirect and direct manners

H Lei, K Schmidt-Bleek, A Dienelt, P Reinke… - Frontiers in …, 2015 - frontiersin.org
Regulatory T cells (Tregs) offer new immunotherapeutic options to control undesired
immune reactions, such as those in transplant rejection and autoimmunity. In addition, tissue …

Immune cells and molecular networks in experimentally induced pulpitis

E Renard, A Gaudin, G Bienvenu… - Journal of dental …, 2016 - journals.sagepub.com
Dental pulp is a dynamic tissue able to resist external irritation during tooth decay by using
immunocompetent cells involved in innate and adaptive responses. To better understand …

Heme oxygenase-1 ameliorates dextran sulfate sodium-induced acute murine colitis by regulating Th17/Treg cell balance

L Zhang, Y Zhang, W Zhong, C Di, X Lin… - Journal of Biological …, 2014 - ASBMB
Inflammatory bowel disease (IBD), including ulcerative colitis and Crohn's disease, is a
group of autoimmune diseases characterized by nonspecific inflammation in the …

Molecular characterization of redox mechanisms in allergic asthma

L Jiang, PT Diaz, TM Best, JN Stimpfl, F He… - Annals of Allergy, Asthma …, 2014 - Elsevier
Objective To investigate the molecular redox mechanisms in allergic asthma and to examine
current studies of the disease to provide a basis for further investigation of oxidative stress in …

Exploring the role of soluble factors associated with immune regulatory properties of mesenchymal stem cells

ÊJ Bassi, DC de Almeida, PMM Moraes-Vieira… - Stem Cell Reviews and …, 2012 - Springer
Mesenchymal stem cells (MSCs) are characterized as multipotent stromal cells with the
capacity for both self-renewal and differentiation into mesodermal cell lineages. MSCs also …

Mesenchymal stem cell-based bioengineered constructs: foreign body response, cross-talk with macrophages and impact of biomaterial design strategies for pelvic …

S Mukherjee, S Darzi, K Paul… - Interface …, 2019 - royalsocietypublishing.org
An excessive foreign body response (FBR) has contributed to the adverse events associated
with polypropylene mesh usage for augmenting pelvic organ prolapse surgery …

Heme oxygenase, inflammation, and fibrosis: the good, the bad, and the ugly?

DMS Lundvig, S Immenschuh… - Frontiers in …, 2012 - frontiersin.org
Upon injury, prolonged inflammation and oxidative stress may cause pathological wound
healing and fibrosis, leading to formation of excessive scar tissue. Fibrogenesis can occur in …

Immune modulation by inhibitors of the HO system

A Fernández-Fierro, SC Funes, M Rios… - International Journal of …, 2020 - mdpi.com
The heme oxygenase (HO) system involves three isoforms of this enzyme, HO-1, HO-2, and
HO-3. The three of them display the same catalytic activity, oxidating the heme group to …