Therapeutic enzymes: discoveries, production and applications

S Tandon, A Sharma, S Singh, S Sharma… - Journal of Drug Delivery …, 2021 - Elsevier
Enzymes today play a predominant role in the pharmaceutical industries due to their ability
to efficiently and selectively catalyze biochemical reactions in living systems. Since the …

Hacking the immune response to solid tumors: harnessing the anti-cancer capacities of oncolytic bacteria

JM Roe, K Seely, CJ Bussard, E Eischen Martin… - Pharmaceutics, 2023 - mdpi.com
Oncolytic bacteria are a classification of bacteria with a natural ability to specifically target
solid tumors and, in the process, stimulate a potent immune response. Currently, these …

Isolation, production, purification, assay and characterization of fibrinolytic enzymes (Nattokinase, Streptokinase and Urokinase) from bacterial sources

R Dubey, J Kumar, D Agrawala, T Char… - African Journal of …, 2011 - ajol.info
Abstract Nattokinase, Streptokinase and Urokinase are novel fibrinolytic enzymes which are
isolated from Bacillus subtilis, β-haemolytic Streptococci and urine sample. The fibrinolytic …

Streptokinase: an efficient enzyme in cardiac medicine

MA Zia - Protein and Peptide Letters, 2020 - ingentaconnect.com
An imbalance in oxygen supply to cardiac tissues or formation of thrombus leads to
deleterious results like pulmonary embolism, coronary heart disease and acute cardiac …

[HTML][HTML] Maggot kinase: A novel and cost-effective fibrinolytic enzyme from maggots

C Liu, H Sun, S Zhang, X Li, L Ma - International Journal of Biological …, 2024 - Elsevier
Maggot kinase, a novel fibrinolytic enzyme source, has been isolated from fly maggots and
comprehensively characterized. Using CM-52 ion exchange chromatography and affinity …

Mechanisms that potentially contribute to the development of post-streptococcal glomerulonephritis

MR Munif, RA Hart, RAM Rafeek… - Pathogens and …, 2024 - academic.oup.com
Post-streptococcal glomerulonephritis (PSGN) is primarily associated with preceding group
A streptococcal skin or throat infections, now mainly observed in economically …

Enhanced production of streptokinase by chemical mutagenesis of streptococcus agalactiae EBL-20

A Arshad, MA Zia, M Asghar, FA Joyia - Brazilian Archives of Biology …, 2019 - SciELO Brasil
Streptokinase (SK) is an enzyme that is used for the treatment of cardiovascular diseases.
The current study focused on the enhanced production of SK by inducing mutation in …

Focalization of thrombosis and therapeutic perspectives: A memoir

S Merlyn Keziah, C Subathra Devi - Oriental Pharmacy and Experimental …, 2018 - Springer
The main aim of the review is to recapitulate the effects of thrombotic diseases, clotting
disorders, and the methodology of prospecting a range of thrombolytics from various …

Streptokinase production from Streptococcus dysgalactiae subsp. equisimilis SK-6 in the presence of surfactants, growth factors and trace elements

S Bhardwaj, J Angayarkanni - 3 Biotech, 2015 - Springer
Streptokinase is an extracellular protein secreted by various strains of streptococci and is
used clinically as an intravenous thrombolytic agent for the treatment of acute myocardial …

[PDF][PDF] Microbial Uricase and its Unique Potential Applications.

K Elbanna, A Alshareef, LA Neyaz… - Advancements of …, 2024 - sciendo.com
The uricase enzyme yields allantoin, hydrogen peroxide, and carbon dioxide by catalyzing
the oxidative opening of the purine ring in the urate pathway. This enzyme is important for …