Vascular endothelial growth factor and its receptor system: physiological functions in angiogenesis and pathological roles in various diseases

M Shibuya - The Journal of Biochemistry, 2013 - academic.oup.com
Vascular endothelial growth factors (VEGFs) belong to the platelet-derived growth factor
supergene family, and they play central roles in the regulation of angiogenesis and …

Resistance to Obesity by Repression of VEGF Gene Expression through Induction of Brown-Like Adipocyte Differentiation

X Lu, Y Ji, L Zhang, Y Zhang, S Zhang, Y An… - …, 2012 - academic.oup.com
Adipose tissues are classified into white adipose tissue (WAT) and brown adipose tissue
(BAT). WAT is responsible for energy storage, and malfunction is associated with obesity …

VEGF and VEGFB play balancing roles in adipose differentiation, gene expression, and function

H Jin, D Li, X Wang, J Jia, Y Chen, Y Yao… - …, 2018 - academic.oup.com
Obesity is the result of abnormal adipose development and energy metabolism. Using
vascular endothelial growth factor (VEGF) B–knockout and inducible VEGF downregulation …

Effects of preterm birth and ventilation on glomerular capillary growth in the neonatal lamb kidney

MR Sutherland, D Ryan, MJ Dahl… - Journal of …, 2016 - journals.lww.com
Objectives: Preterm birth is linked to the development of hypertension later in life. This may
relate to impaired glomerular capillary growth following preterm birth. The aim of this study …

Effect of low VEGF on lung development and function

MZZ Myint, J Jia, S Adlat, ZM Oo, H Htoo, F Hayel… - Transgenic …, 2021 - Springer
Vascular endothelial growth factor (VEGF) is important for lung development and function
but ideal mouse models are limited to decipher the quantitative relationship between VEGF …

Transcriptional profiling of mouse uterus at pre-implantation stage under VEGF repression

Y Ji, X Lu, Q Zhong, P Liu, Y An, Y Zhang, S Zhang… - PLoS …, 2013 - journals.plos.org
Uterus development during pre-implantation stage affects implantation process and embryo
growth. Aberrant uterus development is associated with many human reproductive diseases …

Determination of the physiological and pathological roles of E2F3 in adult tissues

I Gamper, DL Burkhart, MJ Bywater, D Garcia… - Scientific Reports, 2017 - nature.com
While genetically engineered mice have made an enormous contribution towards the
elucidation of human disease, it has hitherto not been possible to tune up or down the level …

Repression of adipose vascular endothelial growth factor reduces obesity through adipose browning

Y Chen, M Zhao, T Zheng, S Adlat… - American Journal …, 2019 - journals.physiology.org
Obesity is the result of excessive energy accumulation and is associated with many
diseases. We previously reported that universal repression of vascular endothelial growth …

Renal function and blood pressure: molecular insights into the biology of endothelin-1

N Vignon-Zellweger, S Heiden, N Emoto - Endothelin in Renal …, 2011 - karger.com
The therapeutic implications of the actions of endothelin (ET)-1 upon renal and
cardiovascular function are evident. Among other diseases, ET-1 is recognized to be …

Role of microRNAs in podocyte structure and function

S Meisinger - 2022 - epub.uni-regensburg.de
Improvement of sequencing techniques lead to identification of more than 38.500 miRNAs in
the last decades. In 2019 the human genome contained 2654 mature miRNAs while the …