Adipose tissue dysfunction and obesity-related male hypogonadism

VA Genchi, E Rossi, C Lauriola, R D'Oria… - International Journal of …, 2022 - mdpi.com
Obesity is a chronic illness associated with several metabolic derangements and
comorbidities (ie, insulin resistance, leptin resistance, diabetes, etc.) and often leads to …

Sex differences in fat storage, fat metabolism, and the health risks from obesity: possible evolutionary origins

ML Power, J Schulkin - British journal of nutrition, 2008 - cambridge.org
Human beings are susceptible to sustained weight gain in the modern environment.
Although both men and women can get fat, they get fat in different ways, and suffer different …

[HTML][HTML] Ion channels, phosphorylation and mammalian sperm capacitation

PE Visconti, D Krapf, JL De La Vega-beltrán… - Asian journal of …, 2011 - ncbi.nlm.nih.gov
Sexually reproducing animals require an orchestrated communication between
spermatozoa and the egg to generate a new individual. Capacitation, a maturational …

[HTML][HTML] Semen parameters and hormonal profile in obese fertile and infertile males

ERM Hofny, ME Ali, HZ Abdel-Hafez, EED Kamal… - Fertility and sterility, 2010 - Elsevier
OBJECTIVE: To study the changes in semen parameters, gonadotropic and sex hormones,
and serum leptin in obese fertile and infertile oligozoospermic men. DESIGN: Prospective …

Survival factors regulating ovarian apoptosis--dependence on follicle differentiation

E Markstrom, EC Svensson, R Shao… - …, 2002 - rep.bioscientifica.com
Epigenetic reprogramming plays a pivotal role during embryogenesis, including both
covalent and non-covalent modifications to chromatin. In this study, we investigated the role …

30 years of the mineralocorticoid receptor: the brain mineralocorticoid receptor: a saga in three episodes

M Joëls, ER de Kloet - Journal of Endocrinology, 2017 - joe.bioscientifica.com
In 1968, Bruce McEwen discovered that 3 H-corticosterone administered to
adrenalectomised rats is retained in neurons of hippocampus rather than those of …

[图书][B] The evolution of obesity

ML Power, J Schulkin - 2009 - books.google.com
In this sweeping exploration of the relatively recent obesity epidemic, Michael L. Power and
Jay Schulkin probe evolutionary biology, history, physiology, and medical science to …

Human male gamete endocrinology: 1alpha, 25-dihydroxyvitamin D3 (1, 25 (OH) 2D3) regulates different aspects of human sperm biology and metabolism

S Aquila, C Guido, E Middea, I Perrotta, R Bruno… - Reproductive Biology …, 2009 - Springer
Background A wider biological role of 1alpha, 25-Dihydroxyvitamin D3 (1, 25 (OH) 2D3), the
active metabolite of vitamin D3, in tissues not primarily related to mineral metabolism was …

Signal transduction pathways that regulate sperm capacitation and the acrosome reaction

A Abou-haila, DRP Tulsiani - Archives of biochemistry and biophysics, 2009 - Elsevier
Ejaculated spermatozoa must undergo physiological priming as they traverse the female
reproductive tract before they can bind to the egg's extracellular coat, the zona pellucida …

Implications of leptin in neuroendocrine regulation of male reproduction

D Landry, F Cloutier, LJ Martin - Reproductive biology, 2013 - Elsevier
Obesity is a major health problem contributing to increased subfertility in males, as well as
increased morbidity for diseases related to a decline in testosterone production with aging …