Neuronal assemblies within the nervous system produce electrical activity that can be
recorded in terms of action potential patterns. Such patterns provide a sensitive endpoint to …

There is a need for methods to screen and prioritize chemicals for potential hazard,
including neurotoxicity. Microelectrode array (MEA) systems enable simultaneous …

In this paper we propose a firing statistics based neuronal network burst detection algorithm
for neuronal networks exhibiting highly variable action potential dynamics. Electrical activity …

Detection and characterization of chemically induced toxic effects in the nervous system
represent a challenge for the hazard assessment of chemicals. In vivo, neurotoxicological …

The last few decades have seen the marketing of hundreds of new pesticide products with a
forecasted expansion of the global agrochemical industry. As several pesticides directly …

Assessing the molecular mechanism of a chemical-biological interaction and bonding
stands as the ultimate goal of any modern quantitative structure-activity relationship (QSAR) …

Pupil is controlled by the autonomous nervous system (ANS). It shows complex movements
and changes of size even in conditions of constant stimulation. The possibility of extracting …

Preconditioning is defined as a range of stimuli that allow cells to withstand subsequent
anaerobic and other deleterious conditions. While cell protection under preconditioning is …

Neuronal avalanches are a ubiquitous form of activity characterized by spontaneous bursts
whose size distribution follows a power-law. Recent theoretical models have replicated …

The authors reexamined reported effects of age, illumination, and stationary visible structure
on the net center of pressure (COP) derived from dual, side-by-side force plates (J. Kinsella …