Cytotoxic drugs have long been recognised to kill cancer cells through apoptosis. According
to a current study, pyroptosis inhibits cell proliferation and shrinks tumors. Pyroptosis and …

Pyroptosis is a type of programmed cell death characterized by cell swelling and osmotic
lysis, resulting in cytomembrane rupture and release of immunostimulatory components …

Head and neck cancer is a malignant tumour with a high mortality rate characterized by late
diagnosis, high recurrence and metastasis rates, and poor prognosis. Head and neck …

Immune checkpoint blockade (ICB) treatment has demonstrated excellent medical effects in
oncology, and it is one of the most sought after immunotherapies for tumors. However, there …

CXC chemokine receptor type 4 (CXCR4) is critical for homeostasis of the adaptive and
innate immune system in some CNS diseases. Bruton's tyrosine kinase (BTK) is an essential …

Colorectal cancer (CRC) remains the third cause of cancer-related mortality in Western
countries, metastases are the main cause of death. CRC treatment remains limited by …

Background There has been widespread concern about the high cancer mortality rate and
the shortcomings of conventional cancer treatments. Immunotherapy is a novel oncology …

While immunotherapy has emerged as a promising strategy to treat melanoma, the limited
availability of immunotherapeutic agents in tumors due to the immunosuppressive tumor …

Among bio-inspired protein materials, secretory protein microparticles are of clinical interest
as self-contained, slow protein delivery platforms that mimic secretory granules of the human …

Nanomedicine is a fast-growing field of nanotechnology. One of the major obstacles for a
wider use of nanomaterials for medical application is the lack of standardized toxicity …