Ageing meets kidney disease

A Ortiz, F Mattace-Raso, MJ Soler… - Clinical Kidney …, 2022 - academic.oup.com
Chronic kidney disease (CKD) is defined as abnormalities of kidney structure or function,
present for˃ 3 months, with implications for health. The most used diagnostic criteria are a …

A prospective study of the association between serum klotho and mortality among adults with rheumatoid arthritis in the USA

Q Che, Q Jia, X Zhang, S Sun, X Zhang… - Arthritis Research & …, 2023 - Springer
Background While it is known that klotho has negative regulatory effects in a variety of
diseases such as metabolic disorders and kidney disease, the specific role of klotho in …

Protective association of Klotho rs495392 gene polymorphism against hepatic steatosis in non-alcoholic fatty liver disease patients

WY Liu, X Zhang, G Li, LJ Tang, PW Zhu… - Clinical and …, 2021 - pmc.ncbi.nlm.nih.gov
Background/Aims Non-alcoholic fatty liver disease (NAFLD) is closely associated with
metabolic dysfunction. Among the multiple factors, genetic variation acts as important …

Role of deleterious nsSNPs of klotho protein and their drug response: A computational mechanical insights

JM Jayaraj, K Muthusamy - Journal of Biomolecular Structure and …, 2024 - Taylor & Francis
Worldwide, the burden of chronic kidney disease (CKD) has increased rapidly and is a lethal
disease. The klotho protein plays a vital role in the regulatory mechanism in the progression …

The predictive value of coronary artery calcification score combined with bone mineral density for the 2-year risk of cardiovascular events in maintenance …

J Huang, L Bao, Y Pan, Q Lu, Y Huang, Q Ding… - … Urology and Nephrology, 2022 - Springer
Purpose Cardiovascular disease is the leading cause of death in maintenance hemodialysis
(MHD) patients. The aim of this study is to investigate the predictive value of coronary artery …

The unaccomplished mission of reducing mortality in patients on kidney replacement therapy

A Ortiz - Clinical Kidney Journal, 2020 - academic.oup.com
Six years ago, a comprehensive review by the EURECA-m working group of the ERA-EDTA
thoroughly addressed the drivers of mortality in patients with end-stage kidney disease. Not …

[PDF][PDF] Klotho rs495392 gene polymorphism and non-alcoholic fatty liver disease

W Liu, X Zhang, G Li, L Tang, P Zhu, R Rios… - … Mechanisms of Fatty …, 2022 - pure.eur.nl
Abstract Background & Aims: Non-alcoholic fatty liver disease (NAFLD) is closely associated
with metabolic dysfunction. Among the multiple factors, genetic variation acts as important …

[PDF][PDF] Protective association of Klotho rs495392 gene polymorphism against

WY Liu, X Zhang, G Li, LJ Tang, PW Zhu - scholar.archive.org
Methods: We evaluated the impact of the KL rs495392 polymorphism on liver histology in
531 Chinese with NAFLD and replicated that in the population-based Rotterdam Study …