It is important to understand the balance between cortical plasticity and stability in various
systems and across spatial scales in the adult brain. Here we review studies of adult …

There is an ongoing debate about whether adult human primary visual cortex (V1) is
capable of large-scale cortical reorganization in response to bilateral retinal lesions. Animal …

Human studies addressing the long-term effects of peripheral retinal degeneration on visual
cortical function and structure are scarce. Here we investigated this question in patients with …

Purpose.: During measurement with functional MRI (fMRI) during passive viewing, subjects
with macular degeneration (MD) have a large unresponsive lesion projection zone (LPZ) in …

Over the past 15 years, techniques for identifying visual areas using magnetic resonance
imaging (MRI) in human subjects have been applied widely to multiple populations. This …

Visual cortical plasticity induced by overt retinal lesions (scotomas) has remained a
controversial phenomenon. Here we studied cortical plasticity in a silent model of retinal …

Background Macular degeneration (MD) is one of the most frequent causes of visual deficit,
resulting in alterations affecting not only the retina but also the entire visual pathway up to …

Purpose In patients with central visual field scotomata, a large part of visual cortex is not
adequately stimulated. Patients often use a new eccentric fixation area on intact peripheral …

The purpose of this study was to use functional magnetic resonance imaging (fMRI) to
investigate the response of the visual cortex to unilateral primary open-angle glaucoma …

Visual field defects that arise from eye disease are increasing as human life spans lengthen.
The consequences of visual field defects on the central visual pathways are important to …