The role of nanotechnology in the treatment of viral infections

L Singh, HG Kruger, GEM Maguire… - Therapeutic …, 2017 - journals.sagepub.com
Infectious diseases are the leading cause of mortality worldwide, with viruses in particular
making global impact on healthcare and socioeconomic development. In addition, the rapid …

Application of gold nanoparticles in biomedical and drug delivery

H Daraee, A Eatemadi, E Abbasi… - Artificial cells …, 2016 - Taylor & Francis
Nanoparticles are the simplest form of structures with sizes in the nanometer (nm) range. In
principle any collection of atoms bonded together with a structural radius of< 100 nm can be …

Quantifying nanoparticle cellular uptake: which method is best?

B Drasler, D Vanhecke, L Rodriguez-Lorenzo… - …, 2017 - Taylor & Francis
Commentary Drasler, Vanhecke, Rodriguez-Lorenzo, Petri-Fink & Rothen-Rutishauser
fication per se can have quite different meanings. In general, quantification is described as …

Investigation of gold nanoparticle radiosensitization mechanisms using a free radical scavenger and protons of different energies

JCG Jeynes, MJ Merchant, A Spindler… - Physics in Medicine …, 2014 - iopscience.iop.org
Gold nanoparticles (GNPs) have been shown to sensitize cancer cells to x-ray radiation,
particularly at kV energies where photoelectric interactions dominate and the high atomic …

Thin film depth profiling by ion beam analysis

C Jeynes, JL Colaux - Analyst, 2016 - pubs.rsc.org
The analysis of thin films is of central importance for functional materials, including the very
large and active field of nanomaterials. Quantitative elemental depth profiling is basic to …

Intercomparison of radiosensitization induced by gold and iron oxide nanoparticles in human glioblastoma cells irradiated by 6 MV photons

DB Guerra, EMN Oliveira, AR Sonntag, P Sbaraine… - Scientific Reports, 2022 - nature.com
In this work, an intercomparison of sensitization effects produced by gold (GNP) and dextran-
coated iron oxide (SPION-DX) nanoparticles in M059J and U87 human glioblastoma cells …

Sources of variability in nanoparticle uptake by cells

C Åberg, V Piattelli, D Montizaan, A Salvati - Nanoscale, 2021 - pubs.rsc.org
Understanding how nano-sized objects are taken up by cells is important for applications
within medicine (nanomedicine), as well as to avoid unforeseen hazard due to …

Cross-correlative single-cell analysis reveals biological mechanisms of nanoparticle radiosensitization

T Turnbull, M Douglass, NH Williamson, D Howard… - ACS …, 2019 - ACS Publications
Nanoparticle radiosensitization has been demonstrated well to enhance the effects of
radiotherapy, motivate the improvement of therapeutic ratios, and decrease morbidity in …

Kinetics of nanoparticle uptake into and distribution in human cells

C Åberg - Nanoscale advances, 2021 - pubs.rsc.org
Whether one wishes to optimise drug delivery using nano-sized carriers or avoid hazard
posed by engineered nanomaterials, the kinetics of nanoparticle uptake into human cells …

Modelling direct DNA damage for gold nanoparticle enhanced proton therapy

M Sotiropoulos, NT Henthorn, JW Warmenhoven… - Nanoscale, 2017 - pubs.rsc.org
Gold nanoparticles have been proven as potential radiosensitizer when combined with
protons. Initially the radiosensitization effect was attributed to the physical interactions of …