Potential and therapeutic roles of diosmin in human diseases
E Huwait, M Mobashir - Biomedicines, 2022 - mdpi.com
Because of their medicinal characteristics, effectiveness, and importance, plant-derived
flavonoids have been a possible subject of research for many years, particularly in the last …
flavonoids have been a possible subject of research for many years, particularly in the last …
Pivotal role of glycogen synthase kinase-3: a therapeutic target for Alzheimer's disease
Neurodegenerative diseases are among the most challenging diseases with poorly known
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
mechanism of cause and paucity of complete cure. Out of all the neurodegenerative …
Synthesis of silver nano particles using myricetin and the in-vitro assessment of anti-colorectal cancer activity: In-silico integration
The creation of novel anticancer treatments for a variety of human illnesses, including
different malignancies and dangerous microbes, also potentially depends on nanoparticles …
different malignancies and dangerous microbes, also potentially depends on nanoparticles …
NF-kB in signaling patterns and its temporal dynamics encode/decode human diseases
S Almowallad, LS Alqahtani, M Mobashir - Life, 2022 - mdpi.com
Defects in signaling pathways are the root cause of many disorders. These malformations
come in a wide variety of types, and their causes are also very diverse. Some of these flaws …
come in a wide variety of types, and their causes are also very diverse. Some of these flaws …
Multi-staged gene expression profiling reveals potential genes and the critical pathways in kidney cancer
Cancer is among the highly complex disease and renal cell carcinoma is the sixth-leading
cause of cancer death. In order to understand complex diseases such as cancer, diabetes …
cause of cancer death. In order to understand complex diseases such as cancer, diabetes …
Myeloid maturation potentiates STAT3-mediated atypical IFN-γ signaling and upregulation of PD-1 ligands in AML and MDS
Interferon (IFN)-γ is the major mediator of anti-tumor immune responses; nevertheless,
cancer cells use intrigue strategies to alter IFN-γ signaling and avoid elimination …
cancer cells use intrigue strategies to alter IFN-γ signaling and avoid elimination …
An approach for systems-level understanding of prostate cancer from high-throughput data integration to pathway modeling and simulation
M Mobashir, SP Turunen, MA Izhari, IM Ashankyty… - Cells, 2022 - mdpi.com
To understand complex diseases, high-throughput data are generated at large and multiple
levels. However, extracting meaningful information from large datasets for comprehensive …
levels. However, extracting meaningful information from large datasets for comprehensive …
A network-guided approach to discover phytochemical-based anticancer therapy: Targeting MARK4 for hepatocellular carcinoma
S Ahmed, M Mobashir, LA Al-Keridis… - Frontiers in …, 2022 - frontiersin.org
MAP/microtubule affinity-regulating kinase 4 (MARK4) is associated with various biological
functions, including neuronal migration, cell polarity, microtubule dynamics, apoptosis, and …
functions, including neuronal migration, cell polarity, microtubule dynamics, apoptosis, and …
Rlm1 mediates positive autoregulatory transcriptional feedback that is essential for Slt2-dependent gene expression
Activation of the yeast cell wall integrity (CWI) pathway induces an adaptive transcriptional
programme that is largely dependent on the transcription factor Rlm1 and the mitogen …
programme that is largely dependent on the transcription factor Rlm1 and the mitogen …
Gene Expression Profiling of Early Acute Febrile Stage of Dengue Infection and Its Comparative Analysis With Streptococcus pneumoniae Infection
Infectious diseases are the disorders caused by organisms such as bacteria, viruses, fungi,
or parasites. Although many of them are permentantly hazardous, a number of them live in …
or parasites. Although many of them are permentantly hazardous, a number of them live in …