DNAzyme-based biosensors: Immobilization strategies, applications, and future prospective

S Khan, B Burciu, CDM Filipe, Y Li, K Dellinger… - Acs Nano, 2021 - ACS Publications
Since their discovery almost three decades ago, DNAzymes have been used extensively in
biosensing. Depending on the type of DNAzyme being used, these functional …

The role of miRNAs in ovarian cancer pathogenesis and therapeutic resistance–a focus on signaling pathways interplay

A Ismail, AI Abulsoud, D Fathi, A Elshafei… - … -Research and Practice, 2022 - Elsevier
One of the most prevalent and lethal forms of gynecological cancer is ovarian cancer (OC),
which is often diagnosed in its latter, deadly stages. The OC's high mortality and …

Circular RNA circ-CPA4/let-7 miRNA/PD-L1 axis regulates cell growth, stemness, drug resistance and immune evasion in non-small cell lung cancer (NSCLC)

W Hong, M Xue, J Jiang, Y Zhang, X Gao - Journal of Experimental & …, 2020 - Springer
Background Non-small cell lung cancer (NSCLC) cells derived intracellular and extracellular
programmed cell death ligand 1 (PD-L1) promoted cancer progression and drug resistance …

Circulating microRNAs: Biomarkers of disease

Y Wu, Q Li, R Zhang, X Dai, W Chen, D Xing - Clinica Chimica Acta, 2021 - Elsevier
MicroRNAs are a class of endogenous noncoding single-stranded RNA molecules with
approximately 20–24 nucleotides and are associated with a broad range of biological …

miRNA profile in ovarian cancer

S Ghafouri-Fard, H Shoorei, M Taheri - Experimental and molecular …, 2020 - Elsevier
Ovarian cancer is a gynecological cancer with high mortality and a heterogeneous nature
which complicates its early detection and primary prevention. Numerous studies have …

Iron metabolism in the tumor microenvironment—Implications for anti-cancer immune response

A Sacco, AM Battaglia, C Botta, I Aversa, S Mancuso… - Cells, 2021 - mdpi.com
New insights into the field of iron metabolism within the tumor microenvironment have been
uncovered in recent years. Iron promotes the production of reactive oxygen species, which …

Find new channel for overcoming chemoresistance in cancers: Role of stem cells-derived exosomal microRNAs

GM Hussein, SM Mohammed, M Faris… - International Journal of …, 2022 - Elsevier
Chemoresistance has remained a significant concern in tumor recurrence and elevated
cancer-related mortalities. A deep insight into mechanisms by which cancerous cells resist …

Ovarian cancer: epigenetics, drug resistance, and progression

W Xie, H Sun, X Li, F Lin, Z Wang, X Wang - Cancer cell international, 2021 - Springer
Ovarian cancer (OC) is one of the most common malignant tumors in women. OC is
associated with the activation of oncogenes, the inactivation of tumor suppressor genes, and …

Epigenetic biomarkers in the management of ovarian cancer: current prospectives

A Singh, S Gupta, M Sachan - Frontiers in cell and developmental …, 2019 - frontiersin.org
Ovarian cancer (OC) causes significant morbidity and mortality as neither detection nor
screening of OC is currently feasible at an early stage. Difficulty to promptly diagnose OC in …

Roles of microRNAs in ovarian cancer tumorigenesis: two decades later, what have we learned?

AA Alshamrani - Frontiers in oncology, 2020 - frontiersin.org
Ovarian cancer is one of the top gynecological malignancies that cause deaths among
females in the United States. At the molecular level, significant progress has been made in …