[HTML][HTML] Non-cleavable hinge enhances avidity and expansion of CAR-T cells for acute myeloid leukemia

MB Leick, H Silva, I Scarfò, R Larson, BD Choi… - Cancer cell, 2022 - cell.com
Chimeric antigen receptor (CAR) T cell therapy is effective in lymphoid malignancies, but
there has been limited data in myeloid cancers. Here, we start with a CD27-based CAR to …