Microbial secondary metabolites are an important source of antibiotics currently available for combating drug-resistant pathogens. These important secondary metabolites are produced …
B Wei, GA Hu, ZY Zhou, WC Yu, AQ Du, CL Yang… - Microbiome, 2023 - Springer
Background Marine prokaryotes are a rich source of novel bioactive secondary metabolites for drug discovery. Recent genome mining studies have revealed their great potential to bio …
Abstract Virgibacillus salarius 19. PP. SC1. 6 is a coral symbiont isolated from Indonesia's North Java Sea; it has the ability to produce secondary metabolites that provide survival …
Bioprospecting of the marine environment for drug development has gained much attention in recent years owing to its massive chemical and biological diversity. Drugs for the …
R Aminov - Expert Opinion on Drug Discovery, 2022 - Taylor & Francis
Introduction In light of the ever-escalating problem of antimicrobial resistance, there is an urgent need for the development of new antimicrobials. In this review, the role of …
Natural scaffolds remain an important basis for drug development. Therefore, approaches to natural bioactive compound discovery attract significant attention. In this account, we …
N Barzkar, S Sukhikh, O Babich - Frontiers in Microbiology, 2024 - frontiersin.org
The marine environment has remained a source of novel biological molecules with diversified applications. The ecological and biological diversity, along with a unique physical …
JF Fisher, S Mobashery - Marine Drugs, 2023 - mdpi.com
The title of this essay is as much a question as it is a statement. The discovery of the β- lactam antibiotics—including penicillins, cephalosporins, and carbapenems—as largely (if …
A Ali, ET Kang, L Xu - Progress in Organic Coatings, 2024 - Elsevier
Marine biofouling is a major international challenge, which causes significant problems for global ecologies and economies. It manifests as the extensive and costly colonization of …