The role of sex hormones in immune protection of the female reproductive tract

CR Wira, M Rodriguez-Garcia, MV Patel - Nature Reviews Immunology, 2015 - nature.com
Within the human female reproductive tract (FRT), the challenge of protection against
sexually transmitted infections (STIs) is coupled with the need to enable successful …

The role of functional foods, nutraceuticals, and food supplements in intestinal health

A Cencic, W Chingwaru - Nutrients, 2010 - mdpi.com
New eating habits, actual trends in production and consumption have a health,
environmental and social impact. The European Union is fighting diseases characteristic of …

Organoid co-culture model of the human endometrium in a fully synthetic extracellular matrix enables the study of epithelial-stromal crosstalk

JS Gnecco, A Brown, K Buttrey, C Ives, BA Goods… - Med, 2023 - cell.com
Background The human endometrium undergoes recurring cycles of growth, differentiation,
and breakdown in response to sex hormones. Dysregulation of epithelial-stromal …

Mast cells: the Jekyll and Hyde of tumor growth

TC Theoharides, P Conti - Trends in immunology, 2004 - cell.com
Mast cells accumulate in the stroma surrounding certain tumors, especially mammary
adenocarcinoma, and molecules they secrete could benefit the tumor. These include …

Generation of a three-dimensional collagen scaffold-based model of the human endometrium

Y Abbas, LG Brunel, MS Hollinshead… - Interface …, 2020 - royalsocietypublishing.org
The endometrium is the secretory lining of the uterus that undergoes dynamic changes
throughout the menstrual cycle in preparation for implantation and a pregnancy. Recently …

Glycodelin: a major lipocalin protein of the reproductive axis with diverse actions in cell recognition and differentiation

M Seppälä, RN Taylor, H Koistinen… - Endocrine …, 2002 - academic.oup.com
Glycodelin is a glycoprotein that belongs to the lipocalin superfamily. Depending on
glycosylation, glycodelin appears in various isoforms. In the uterus, glycodelin-A is the major …

Osteopontin and Its Receptor αvβ3 Integrin Are Coexpressed in the Human Endometrium during the Menstrual Cycle But Regulated Differentially

KBC Apparao, MJ Murray, MA Fritz… - The Journal of …, 2001 - academic.oup.com
Osteopontin is an arginine-glycine-aspartic acid-containing acidic glycoprotein component
of the extracellular matrix that is postulated to bind to integrin receptors at the cell surface to …

Main actors behind the endometrial receptivity and successful implantation

L Governini, FP Luongo, A Haxhiu, P Piomboni… - Tissue and Cell, 2021 - Elsevier
Embryo implantation occurs during a short period of time, the implantation window, in the
mid-secretory phase of the menstrual cycle. The cross-talk between the endometrium and …

Cancer-associated mutations in endometriosis: shedding light on the pathogenesis and pathophysiology

SW Guo - Human Reproduction Update, 2020 - academic.oup.com
BACKGROUND Endometriosis is a benign gynaecological disease. Thus, it came as a
complete surprise when it was reported recently that the majority of deep endometriosis …

Mechanisms involved in the progression of androgen-independent prostate cancers: it is not only the cancer cell's fault.

JT Arnold, JT Isaacs - Endocrine-related cancer, 2002 - erc.bioscientifica.com
The acquisition of an androgen-independent phenotype by prostate cancer cells is presently
a death sentence for patients. In order to have a realistic chance of changing this outcome …