Developmental programming, a pathway to disease

V Padmanabhan, RC Cardoso… - Endocrinology, 2016 - academic.oup.com
Accumulating evidence suggests that insults occurring during the perinatal period alter the
developmental trajectory of the fetus/offspring leading to long-term detrimental outcomes …

In utero origins of hypertension: mechanisms and targets for therapy

JS Morton, CL Cooke, ST Davidge - Physiological reviews, 2016 - journals.physiology.org
The developmental origins of health and disease theory is based on evidence that a
suboptimal environment during fetal and neonatal development can significantly impact the …

Developmental programming of the female reproductive system—a review

S Yao, J Lopez-Tello… - Biology of …, 2021 - academic.oup.com
Exposures to adverse conditions in utero can lead to permanent changes in the structure
and function of key physiological systems in the developing fetus, increasing the risk of …

Developmental programming of reproduction in the female animal

V Akbarinejad, RA Cushman - Animal Reproduction Science, 2024 - Elsevier
Successful reproduction is a cornerstone in food animal industry in order to sustain food
production for human. Therefore, various methods focusing on genetics and postnatal …

The effect of pre-breeding vitamin E and selenium injection on reproductive performance, antioxidant status, and progesterone concentration in estrus-synchronized …

A Farahavar, Z Rostami, D Alipour… - Tropical animal health and …, 2020 - Springer
The present study was conducted to assess the effects of pre-breeding vitamin E and
selenium (ESe) injections on the reproductive performance, antioxidant status, and serum …

Circadian and seasonal changes in the expression of clock genes in the ovine pars tuberalis.

K Wojtulewicz, M Tomczyk, M Wójcik… - Journal of Animal & …, 2023 - search.ebscohost.com
The pars tuberalis (PT) is part of the pituitary that expresses melatonin receptors, therefore it
is suggested that PT mediates the effect of melatonin on neuroendocrine functions and may …

Developmental programming of fertility in livestock

RA Cushman, GA Perry - Veterinary Clinics: Food Animal …, 2019 - vetfood.theclinics.com
Developmental programming has been studied extensively for its role in preventing offspring
from expressing their total genetic potential for growth owing to stress and insults suffered …

Ovarian and uterine characteristics and onset of puberty in adolescent offspring: Effects of maternal diet and selenium supplementation in sheep

AT Grazul-Bilska, TL Neville, E Borowczyk, A Sharma… - Theriogenology, 2014 - Elsevier
The aim of this study was to determine the effects of maternal diet with adequate (A) or high
(H) selenium (Se) supplementation on ovarian and uterine characteristics, and onset of …

Maternal protein restriction impairs nutrition and ovarian histomorphometry without changing p38MAPK and PI3K-AKT-mTOR signaling in adult rat ovaries

LS Côrtes, HS Silveira, LA Lupi, T de Mello Santos… - Life sciences, 2021 - Elsevier
Aims Because an adequate protein supply is detrimental for the maintenance of
folliculogenesis and ovulation, we evaluated the impact of maternal low protein diet on …

Expression of steroidogenic enzymes in placentome of ewes with pregnancy toxemia after two parturition induction methods

G Özalp, CT Ortaç, B Bozkurt… - Journal of the …, 2023 - ejournals.epublishing.ekt.gr
The regulation pattern of important enzymes in placental steroidogenesis and
prostaglandins in ewes with pregnancy toxemia is reviewed. The alterations of gene …