The role of the canine gut microbiome and metabolome in health and gastrointestinal disease

R Pilla, JS Suchodolski - Frontiers in veterinary science, 2020 - frontiersin.org
The gut microbiome contributes to host metabolism, protects against pathogens, educates
the immune system, and, through these basic functions, affects directly or indirectly most …

[HTML][HTML] The world goes bats: living longer and tolerating viruses

V Gorbunova, A Seluanov, BK Kennedy - Cell Metabolism, 2020 - cell.com
For centuries, people believed that bats possessed sinister powers. Bats are thought to be
ancestral hosts to many deadly viruses affecting humans including Ebola, rabies, and most …

Alternative animal models of aging research

S Holtze, E Gorshkova, S Braude… - Frontiers in Molecular …, 2021 - frontiersin.org
Most research on mechanisms of aging is being conducted in a very limited number of
classical model species, ie, laboratory mouse (Mus musculus), rat (Rattus norvegicus …

Recurrent evolution of extreme longevity in bats

GS Wilkinson, DM Adams - Biology letters, 2019 - royalsocietypublishing.org
Bats live longer than similar-sized mammals, but the number of lineages that have
independently evolved extreme longevity has not previously been determined. Here we …

Managing batch effects in microbiome data

Y Wang, KA LêCao - Briefings in bioinformatics, 2020 - academic.oup.com
Microbial communities have been increasingly studied in recent years to investigate their
role in ecological habitats. However, microbiome studies are difficult to reproduce or …

Age and sex-associated variation in the multi-site microbiome of an entire social group of free-ranging rhesus macaques

MC Janiak, MJ Montague, CI Villamil, MK Stock… - Microbiome, 2021 - Springer
Background An individual's microbiome changes over the course of its lifetime, especially
during infancy, and again in old age. Confounding factors such as diet and healthcare make …

Microbiome diurnal rhythmicity and its impact on host physiology and disease risk

SP Nobs, T Tuganbaev, E Elinav - EMBO reports, 2019 - embopress.org
Host–microbiome interactions constitute key determinants of host physiology, while their
dysregulation is implicated in a wide range of human diseases. The microbiome undergoes …

Characterization of the bacterial microbiome of non-hematophagous bats and associated ectoparasites from Brazil

MR André, P Ikeda, DAB Lee, RB do Amaral… - Frontiers in …, 2023 - frontiersin.org
Introduction Bats, along with their ectoparasites, harbor a wide diversity of symbiotic and
potential pathogenic bacteria. Despite the enormous diversity of bats (181 species), few …

Longitudinal comparative transcriptomics reveals unique mechanisms underlying extended healthspan in bats

Z Huang, CV Whelan, NM Foley, D Jebb… - Nature ecology & …, 2019 - nature.com
Bats are the longest-lived mammals, given their body size. However, the underlying
molecular mechanisms of their extended healthspans are poorly understood. To address …

Seasonal changes in gut microbiota diversity and composition in the greater horseshoe bat

G Xiao, S Liu, Y Xiao, Y Zhu, H Zhao, A Li, Z Li… - Frontiers in …, 2019 - frontiersin.org
A large number of microorganisms colonize the intestines of animals. The gut microbiota
plays an important role in nutrient metabolism and affects a number of physiological …