Cancer is one of the major healthcare challenges across the globe. Several anticancer
drugs are available on the market but they either lack specificity or have poor safety, severe …

Multidrug‐resistant (MDR) pathogens have created a fatal problem for human health and
antimicrobial treatment. Among the currently available antibiotics, many are inactive against …

Pyrazole derivatives, as a class of heterocyclic compounds, possess unique chemical
structures that confer them with a broad spectrum of pharmacological activities. They have …

Synthesis of some new heterocyclic ring systems incorporated pyrimidine and pyridine
moieties starting from 1-(furan-2-yl)-3-(thiophen-2-yl) chalcone was achieved. The structure …

A library of novel naproxen based 1, 3, 4-oxadiazole derivatives (8–16 and 19–26) has been
synthesized and screened for cytotoxicity as EGFR inhibitors. Among the synthesized …

Abstract A series of 1, 3, 4‐oxadiazole‐1, 2, 3‐triazole hybrids bearing different
pharmacophoric moieties has been designed and synthesized. Their antiproliferative activity …

Amino-4, 6-dimethylpyrazolopyridine was applied as a precursor for the synthesis of some
new pyridopyrazolo-triazine and pyridopyrazolo-triazole derivatives through diazotization …

A novel series of pyrido [2, 3-d] pyrimidines; pyrido [3, 2-e][1, 3, 4] triazolo; and tetrazolo [1, 5-
c] pyrimidines were synthesized via different chemical transformations starting from pyrazolo …

In the current study, we report on the development of novel series of pyrazolo [3, 4-b]
pyridine derivatives (8a-u, 11a-n, and 14a, b) as potential anticancer agents. The prepared …

Antibiotic resistance is one of the most important challenges of the 21st century. However,
the growing understanding of bacterial pathogenesis and cell-to-cell communication has …